| Sažetak | Sindrom iritabilnog crijeva (IBS) je funkcionalni gastrointestinalni poremećaj kojeg karakterizira pojava abdominalne boli i poremećaji motilacije. S obzirom da značajno utječe na kvalitetu života i produktivnost oboljelih, predstavlja veliko opterećenje za zdravstveni sustav. Patofiziologija IBS-a je vrlo kompleksna no psihofizičko stanje i prehrana bogata tzv. FODMAP-ima (fermentabilni oligo-, di-, monosaharidi i polioli) se povezuje s pogoršanjem simptoma. Cilj ovog rada bio je utvrditi karakteristike prehrane i utjecaj psihofizičkog stanja (DASS 21 upitnik) kod jako izraženih gastrointestinalnih simptoma specifičnih za IBS (GSRS-IBS upitnik) u mlađoj odrasloj populaciji. Provedeno je opažajno istraživanje putem online ankete koju je ispunio 171 ispitanik (84, 8 % žena i 15, 2 % muškaraca) prosječne dobi 23 godine. Visoki IBS skor (44-75 bodova) je utvrđen kod 19, 3 % ispitanika. Utvrđena je statistički značajna razlika IBS skora po dobi (p=0, 049), ali ne i po spolu. Ispitanici s visokim IBS skorom imaju značajno izraženije razine stresa (p<0, 001), depresije (p<0, 001) i anksioznosti (p<0, 001). Viši IBS skor značajno korelira s lošijim psihofizičkim stanjem osobe. Viša razina stresa je neovisni čimbenik rizika za viši IBS skor. Rizik za viši IBS skor raste za 27, 2 % po svakom bodu porasta razine stresa (OR=1, 272, 95 % CI=1, 066-1, 519, P=0, 008). Viša konzumacija umaka i gotovih jela pokazuje slabu korelaciju s višim IBS skorom (rho=-0, 157). Također, rizik za viši IBS skor raste za 72, 4 % ukoliko osoba u pravilu preskače obroke (OR=1, 724, 95 % CI=1, 035-2, 871, P=0, 036) dok rizik za viši IBS skor raste za 86, 7 % ukoliko osoba smatra da joj određena hrana smeta i izaziva GIT simptome (OR=1, 867, 95 % CI=1, 166-2, 991, P=0, 009). |
| Sažetak (engleski) | Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder characterized by the abdominal pain
and motility disorders. Given that it significantly affects the quality of life and productivity, it represents great
burden on the healthcare. Pathophysiology of IBS is extremely complex but psychological condition and diet
rich with the so-called FODMAPs (Fermentable Oligo-, Di-, Monosaccharides and Polyols) aggravate the
symptoms. The aim of this study was to determine dietary characteristics and the role of psychophysical
condition (DASS 21 questionnaire) in more pronounced gastrointestinal symptoms specific for IBS (GSRS-IBS
questionnaire) among young adults. An observational online survey was completed by 171 participants (84.8%
women and 15.2% men, median age 23 years). High IBS score (44-75 points) was found in 19.3% of study
participants. IBS score significantly differs by age (p=0.049) but not by sex. Participants with high IBS score
have significantly higher levels of stress (p<0.001), depression (p<0.001) and anxiety (p<0.001). High IBS score
correlates significantly with poorer psychophysical state. Higher stress level represents independent risk factor
for high IBS. The risk for high IBS score grows by 23.2% per each point on the stress level (OR=1.272, 95 %
CI=1.066-1.519, P=0.008). A weak negative correlation was found with the consumption of sauces and ready
meals (rho=-0.157). Additionally, the risk for high IBS score grows by 72.4% if a person often skips meals
(OR=1.724, 95 % CI=1.035-2.871, P=0.036) while the risk for high IBS score grows by 86.7% if a person says
that some foods act as a trigger for gastrointestinal symptoms characteristic for IBS (OR=1.867, 95 % CI=1.166-
2.991, P=0.009). |
