Tooth loss, both partial and complete, is nowadays increasingly solved by the installation of dental implants. Various factors affect the success of therapy, and in this paper one of the most important is stated and that is the correct positioning of the implant in relation to the anatomical variations of the mandible. The goal we want to achieve is to make teeth that will be aesthetically and functionally acceptable. When examining and assessing the patient before the implant phase, we want to follow the prosthetic plan and this often leads us to the fact that we often have to approach the anatomical structures of the lower jaw, whose injury can lead to permanent disturbances in the patient and sometimes life-threatening complications. The implant must be placed in the correct position in the available bone so as not to violate biological and surgical principles. Every clinician who approaches implantation with excellent knowledge of anatomical structures should know how to use radiological diagnostics to assess the quantity and quality of hard and soft tissues and thus determine whether there is enough bone to place dental implants and whether augmentation is needed. With a comprehensive clinical examination and analysis of CBCT images, it is possible to develop guidelines that will achieve optimal results, to conduct therapy in a satisfactory manner for both the therapist and the patient.