prikaz prve stranice dokumenta Comparison of Androgen Receptor, VEGF, HIF-1, Ki67 and MMP9 Expression between Non-Metastatic and Metastatic Stages in Stromal and Tumor Cells of Oral Squamous Cell Carcinoma
  Preuzmi
PDF 2.55 MB
Znanstveni rad - Izvorni znanstveni rad
Comparison of Androgen Receptor, VEGF, HIF-1, Ki67 and MMP9 Expression between Non-Metastatic and Metastatic Stages in Stromal and Tumor Cells of Oral Squamous Cell Carcinoma
Life, 11 (2021), 4; 336. https://doi.org/10.3390/life11040336
Batelja-Vuletić, Lovorka; Tomasović-Lončarić, Cedna; Ceppi, Marcello; Bruzzone, Marco; Fučić, Aleksandra; Krstanac, Karolina; Boras Vučićević, Vanja

Institucijski repozitorij: Repozitorij stomatološkog fakulteta u Zagrebu

Citirajte ovaj rad

Batelja Vuletić, L., Tomasović Lončarić, C., Ceppi, M., Bruzzone, M., Fučić, A., Krstanac, K. i Boras Vučićević, V. (2021). Comparison of Androgen Receptor, VEGF, HIF-1, Ki67 and MMP9 Expression between Non-Metastatic and Metastatic Stages in Stromal and Tumor Cells of Oral Squamous Cell Carcinoma. Life, 11. (4). doi: 10.3390/life11040336

Batelja Vuletić, Lovorka, et al. "Comparison of Androgen Receptor, VEGF, HIF-1, Ki67 and MMP9 Expression between Non-Metastatic and Metastatic Stages in Stromal and Tumor Cells of Oral Squamous Cell Carcinoma." Life, vol. 11, br. 4, 2021. https://doi.org/10.3390/life11040336

Batelja Vuletić, Lovorka, Cedna Tomasović Lončarić, Marcello Ceppi, Marco Bruzzone, Aleksandra Fučić, Karolina Krstanac i Vanja Boras Vučićević. "Comparison of Androgen Receptor, VEGF, HIF-1, Ki67 and MMP9 Expression between Non-Metastatic and Metastatic Stages in Stromal and Tumor Cells of Oral Squamous Cell Carcinoma." Life 11, br. 4 (2021). https://doi.org/10.3390/life11040336

Batelja Vuletić, L., et al. (2021) 'Comparison of Androgen Receptor, VEGF, HIF-1, Ki67 and MMP9 Expression between Non-Metastatic and Metastatic Stages in Stromal and Tumor Cells of Oral Squamous Cell Carcinoma', Life, 11(4). doi: 10.3390/life11040336

Batelja Vuletić L, Tomasović Lončarić C, Ceppi M, Bruzzone M, Fučić A, Krstanac K, i sur.. Comparison of Androgen Receptor, VEGF, HIF-1, Ki67 and MMP9 Expression between Non-Metastatic and Metastatic Stages in Stromal and Tumor Cells of Oral Squamous Cell Carcinoma. Life [Internet]. 10.04.2021. [pristupljeno 10.05.2024.];11(4). doi: 10.3390/life11040336

L. Batelja Vuletić, et al., "Comparison of Androgen Receptor, VEGF, HIF-1, Ki67 and MMP9 Expression between Non-Metastatic and Metastatic Stages in Stromal and Tumor Cells of Oral Squamous Cell Carcinoma", Life, vol. 11, br. 4, Travanj 2021. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:127:914613. [Citirano: 10.05.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:127:914613
Podaci o radu
Naslov (engleski)Comparison of Androgen Receptor, VEGF, HIF-1, Ki67 and MMP9 Expression between Non-Metastatic and Metastatic Stages in Stromal and Tumor Cells of Oral Squamous Cell Carcinoma
AutorLovorka Batelja-Vuletić
AutorCedna Tomasović-Lončarić
AutorMarcello Ceppi
AutorMarco Bruzzone
AutorAleksandra Fučić
AutorKarolina Krstanac
AutorVanja Boras Vučićević
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Autorova ustanovaSveučilište u Zagrebu
Stomatološki fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Dentalna medicina
Sažetak (engleski)
Objectives: Oral squamous cell carcinoma (OSCC) is the most common oral malignancy with low survival as it is very often diagnosed at an advanced stage, which is why the accurate profiling of the tumor is essential. The aim of this study was to, for the first time, compare in OSCC the frequency of AR, VEGF, MMP9, HiF1beta and Ki67 between the non-metastatic and metastatic disease. Materials and Methods: In the study, 96 non-metastatic and 91 metastatic OSCC patients were analysed for AR, VEGF, MMP9, HiF1beta and Ki67 levels by immunohistochemistry. Results: All of the tested biomarkers significantly differed between non-metastatic and metastatic disease. A significant association was found between >/=20% AR positive epithelium cells in cytoplasm, Ki67 and VEGF in cancer stroma. Ki67, HiF1beta, VEGF and MMP9 were significantly associated with TNM stages. Conclusion: Our results show for the first time an interplay between AR, VEGF, MMP9, HiF1beta and Ki67 in OSCC which may contribute to better diagnostics and therapy selection.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaLife
Brojčani podacivol. 11, br. 4, 336
e-ISSN2075-1729
DOIhttps://doi.org/10.3390/life11040336
URN:NBNurn:nbn:hr:127:914613
Datum objave publikacije2021-04-10
URL dokumentahttps://www.mdpi.com/2075-1729/11/4/336
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2022-11-10 11:16:04