Periodontal diseases are considered multifactorial chronic inflammatory diseases that can lead to progressive teeth loss. Dentobacterial plaque accumulation is one of the main etiological factors of periodontal diseases. Treatment of such conditions includes various clinical procedures, lifestyle changes and improvement of oral hygiene. Dentobacterial plaque removal and control are considered the main method of prevention and treatment of periodontal diseases. Plaque control involves mechanical and chemical control using a wide variety of currently available oral hygiene products. Mechanical plaque control refers to use of a manual or electric toothbrush and interdental cleaning devices. There are many variations in design and size of manual and electric toothbrushes. Electric toothbrushes, depending on the type of movement, can be oscillatingvibrating and sonic. Chemical control of plaque is used in addition to mechanical control, using various toothpastes and mouthwashes with anti-inflammatory, antibacterial and other effects. In order to achieve satisfactory prevention and treatment of periodontal diseases, motivation and education of patients by therapists are extremely important. It is considered that thoroughly, individually educated patients show better plaque control efficiency, and thus more effective treatment and prevention of periodontal diseases. Manual and electric toothbrushes are considered effective in reducing plaque and gingival inflammation. However, in patients with periodontal disease, oscillating-vibrating electric toothbrushes have an advantage over manual and other electric toothbrushes. Researches have shown that oscillating-vibrating electric toothbrushes provide significant improvement in the indices of plaque and gingival inflammation compared to manual toothbrushes.