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Inflammatory Biomarkers Affecting Survival Prognosis in Patients Receiving Veno-Venous ECMO for Severe COVID-19 Pneumonia
Diagnostics, 13 (2023), 13; 2203. https://doi.org/10.3390/diagnostics13132203
Drmić, Željka; Bandić, Ivan; Hleb, Sonja; Kukoč, Andrea; Sakan, Sanja; Sojčić, Nataša; Kristović, Darko; Mikecin, Verica; Presečki, Ivana; Oremuš, Zrinka Šafarić; Bradić, Nikola; Peršec, Jasminka; Šribar, Andrej

Institucijski repozitorij: Repozitorij stomatološkog fakulteta u Zagrebu

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Drmić, Ž., Bandić, I., Hleb, S., Kukoč, A., Sakan, S., Sojčić, N. ... Šribar, A. (2023). Inflammatory Biomarkers Affecting Survival Prognosis in Patients Receiving Veno-Venous ECMO for Severe COVID-19 Pneumonia. Diagnostics, 13. (13). doi: 10.3390/diagnostics13132203

Drmić, Željka, et al. "Inflammatory Biomarkers Affecting Survival Prognosis in Patients Receiving Veno-Venous ECMO for Severe COVID-19 Pneumonia." Diagnostics, vol. 13, br. 13, 2023. https://doi.org/10.3390/diagnostics13132203

Drmić, Željka, Ivan Bandić, Sonja Hleb, Andrea Kukoč, Sanja Sakan, Nataša Sojčić, Darko Kristović, et al. "Inflammatory Biomarkers Affecting Survival Prognosis in Patients Receiving Veno-Venous ECMO for Severe COVID-19 Pneumonia." Diagnostics 13, br. 13 (2023). https://doi.org/10.3390/diagnostics13132203

Drmić, Ž., et al. (2023) 'Inflammatory Biomarkers Affecting Survival Prognosis in Patients Receiving Veno-Venous ECMO for Severe COVID-19 Pneumonia', Diagnostics, 13(13). doi: 10.3390/diagnostics13132203

Drmić Ž, Bandić I, Hleb S, Kukoč A, Sakan S, Sojčić N, i sur.. Inflammatory Biomarkers Affecting Survival Prognosis in Patients Receiving Veno-Venous ECMO for Severe COVID-19 Pneumonia. Diagnostics [Internet]. 28.06.2023. [pristupljeno 02.12.2024.];13(13). doi: 10.3390/diagnostics13132203

Ž. Drmić, et al., "Inflammatory Biomarkers Affecting Survival Prognosis in Patients Receiving Veno-Venous ECMO for Severe COVID-19 Pneumonia", Diagnostics, vol. 13, br. 13, Lipanj 2023. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:127:362542. [Citirano: 02.12.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:127:362542
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Naslov (engleski)Inflammatory Biomarkers Affecting Survival Prognosis in Patients Receiving Veno-Venous ECMO for Severe COVID-19 Pneumonia
AutorŽeljka Drmić
AutorIvan Bandić
AutorSonja Hleb
AutorAndrea Kukoč
AutorSanja Sakan
AutorNataša Sojčić
AutorDarko Kristović
AutorVerica Mikecin
AutorIvana Presečki
AutorZrinka Šafarić Oremuš
AutorNikola Bradić
AutorJasminka Peršec
AutorAndrej Šribar
Autorova ustanova(Klinička bolnica Dubrava)
Autorova ustanovaSveučilište u Zagrebu
Stomatološki fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
Severe COVID-19 pneumonia in which mechanical ventilation is unable to achieve adequate gas exchange can be treated with veno-venous ECMO, eliminating the need for aggressive mechanical ventilation which might promote ventilator-induced lung injury and increase mortality. In this retrospective observational study, 18 critically ill COVID-19 patients who were treated using V-V ECMO during an 11-month period in a tertiary COVID-19 hospital were analyzed. Biomarkers of inflammation and clinical features were compared between survivors and non-survivors. Survival rates were compared between patients receiving ECMO and propensity matched mechanically ventilated controls. There were 7 survivors and 11 non-survivors. The survivors were significantly younger, with a higher proportion of females, higher serum procalcitonin at ICU admission, and before initiation of ECMO they had significantly lower Murray scores, PaCO2, WBC counts, serum ferritin levels, and higher glomerular filtration rates. No significant difference in mortality was found between patients treated with ECMO compared to patients treated using conventional lung protective ventilation. Hypercapnia, leukocytosis, reduced glomerular filtration rate, and increased serum ferritin levels prior to initiation of V-V ECMO in patients with severe COVID-19 pneumonia may be early warning signs of reduced chance of survival. Further multicentric studies are needed to confirm these findings.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaDiagnostics
Brojčani podacivol. 13, br. 13, 2203
e-ISSN2075-4418
DOIhttps://doi.org/10.3390/diagnostics13132203
URN:NBNurn:nbn:hr:127:362542
Datum objave publikacije2023-06-28
URL dokumentahttps://www.mdpi.com/2075-4418/13/13/2203
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2023-08-21 08:03:48