For many years, ceramo-metal restorations were considered the gold standard for making crowns and fixed partial dentures. Although it proved to be relatively durable and reliable, due to certain problems with this system, the search for more perfect materials continued. The increased aesthetic demands of modern society have led to the fact that metals are being thrown out more and more, so in layered systems, to achieve strength the metal core was substituted with a high-strength ceramic core. However, despite superior aesthetic results with all-ceramic systems, one of the main problems of layered systems has not been eliminated – chipping of veneering ceramics. The weak point of all layered restorations is the interface of two materials. Chippins is a multifactorial problem. In modern prosthodontics, monolithic ceramic restorations have become an adequate alternative to established systems, and in some cases they are even a better solution. The development of CAD/CAM technology accelerates their progress and integration into everyday practice. Monolithic restorations consist entirely of one type of ceramic and are made in one piece, which avoids the most common complication of layered systems, i.e. chipping. They are ususally made of lithium-disilicate and zirconium oxide ceramics. Lithium-disilicate is characterized by favorable aesthetic properties, so it is usually used in the reconstruction of front teeth, while zirconium oxide is characterized by better mechanical properties, so it is more often the material of choice for making restorations on the back teeth and for multi-unit restorations in the area of higher masticatory forces. However, it should be noted that modern zirconium oxide ceramics with an increased degree of translucency are also suitable for the restoration of front teeth. The aim of this paper is to present ceramic materials for monolithic restorations in fixed prosthodontics, their properties, indications and contraindications for their use, the specifics of tooth preparation for monolithic restorations, cementation procedures, and the advantages and disadvantages of monolithic restorations compared to layered restorations.