Bruxism is a daytime or nighttime locomotor system disorder characterized by clenching, pounding, or grinding of the teeth. This leads to increased activity in the masticatory muscles, resulting in abnormal movements of the lower jaw and within the temporomandibular joint. The loss of hard dental tissues and reduced vertical dimension of occlusion, as a consequence of bruxism, represent a challenge in clinical work. The purpose of this paper is to present the modern possibilities of oral rehabilitation of patients with bruxism. A detailed course of the therapeutic procedure for the patients mentioned above is described. First, using analog and digital technologies, an occlusal splint was fabricated for the patient to prepare the masticatory system for prosthetic therapy. Then, the prosthetic work was planned with a mock-up, office and laboratory temporary prosthetic works were made, and finally, a definitive prosthetic work was created using monolithic zirconium oxide ceramics. The complete rehabilitation of bruxism patients treated with faceted and non-faceted zirconia restorations with increased VDO has been scarcely investigated, therefore, further studies are needed. After cementing the definitive prosthetic work, the patient received a new occlusal splint for the purpose of symptomatic treatment of bruxism.