Oropharyngeal tumors are classified into the group of head and neck tumors, which are the sixth most common tumors worldwide. There are two types of oropharyngeal tumors: benign and malignant tumors. In the last few decades an increase in the incidence of oropharyngeal cancer has been noted, while the number of other head and neck tumors stagnates or declines. Although most oropharyngel cancers are diagnosed in middle and older- aged men who smoke and consume alcohol, there is an increase in the incidence of oropharyngeal cancer in people younger than 45. The occurence of cancer among younger population is associated with human papiloma virus infection (HPV). HPV- positive oropharyngeal tumors are more suitable for treatment and have significantly higher survival rate than HPV- negative tumors. Any patient with symptoms suggesting oropharyngeal cancer should be referred to an otolaryngologist for further evaluation including physical and endoscopic examination, biopsy and radiological examination. When oropharyngeal tumor is diagnosed the treatment options depend on the stage of the disease, and the best results are achieved through a multidisciplinary approach. The team involved in the treatment consists of otolaryngologist, oncologist, radiologist, pathologist, anesthesiologist, speech therapist, nutritionist, psychologist and dentist. In many cases, patients come to a doctor with advanced tumors, and the most common symptoms are sore throat and a lump in the neck. The treatment of advanced cancers often requires extensive surgery which results in major defects and reduced quality of life. Therefore, an early recognition of tumor is a prerequisite for successful treatment and favourable prognosis.