Partial edentulism implies lack of multiple teeth. Teeth are part of a complex masticatory system, so their lack leads to disruption of the aesthetics and functions of the entire system. Timely prosthetic therapy is of great importance. When planning therapy, it is important to consider the classification of partial edentulism, with the Kennedy classification being the most commonly used. Removable partial denture, fixed-removable (combined) restorations, fixed dental prostheses and implant-supported prostheses might be used as prosthetic solutions for partial edentulism. The choice of an individual therapeutic solution will depend on the number, location and quality of the remaining teeth, but also on the patient's health condition and his financial capabilities. In cases of financial constraints, a partial denture is often considered the best solution. Removable partial denture with metal base is most often used because it provides better strength and stability compared to an acrylic partial denture. The problem of the aesthetics of a classic partial denture retained with clasps is solved by using fixedremovable (combined) restoration. It consists of a fixed and a mobile part that are interconnected by various types of attachments. The fixed bridge represents a long-lasting aesthetic, masticatory-functional and phonetic therapeutic solution, and dental implants are an ideal choice in situations where the general condition and financial capabilities of the patient are not limiting factors. The purpose of this study was to review current knowledge on the impact of different solutions of partial edentulism on the Oral Health-related Quality of Life. For that purpose, the various available studies on that subject have been studied and presented.