Communication is the transmission of information through a specific communication channel. Communication is precisely what differentiates humans from animals and makes them social beings. From birth, children begin to interact with the world and learn from the people around them and the people they meet. Down syndrome, as one of the very common genetic disorders, creates various difficulties in communication to children and people with this syndrome, but also to everyone they communicate with. The aim of this paper is communication of children with Down Syndrome within kindergarten group. To highlight the difficulties that children with DS experience, both in kindergarten and in everyday life. Working with children within the kindergarten group is briefly explained, suggestions on how to act to facilitate communication with children with this syndrome. Special emphasis is given to the development of speech that is essential in communication, how to develop communication and socialization of children with Down syndrome through speech. Finally, to point out the importance of cooperation between parents and kindergartens for the development of children's communication with Down Syndrome.