Society has changed its relation towards children with developmental disabilities from pure discriminatory approaches to those practicing full integration into society and realizing the children’ educational rights. The education system changes its viewpoint on children with developmental disabilities in relation to society’s attitude towards them. Contemporary education systems in Croatia as well as the rest of the world are based on the principles of integration and inclusion. Such policies are emphatic about the importance of including the children with developmental disabilities into regular classes, implementing the necessary adjustments depending on the needs of the individual pupil. This paper lists a spectre of developmental disabilities and shows how to integrate children with developmental disabilities into regular education system especially reflecting at kinesiology programme with physical activities adjusted to their needs. Physical activity has a positive impact on psychomotor development and successful socialization of children with developmental disabilities. In PE classes children are especially motivated when looking hidden objects, collecting them or finishing an activity where they change the look of something. In regard to this, a competent teacher is vital in designing the programme individually for every child’s needs. Such a kinesiology programme consists of physical activities and variety of games which are well adapted to the needs of a particular child with developmental disability.