Breast cancer is one of the major public health problems in contemporary societies and it represent the most common cause of death in women among malingnant diseases. It is, also, a disease that is affecting the younger population more often, with increasing incidence for all ages. The most successful strategy in struggle with this disease is prevention and early cancer detection. Lifestyle as well as selfhaelthcare may improve the success of the treatment. For this reason, the need to raise women's awareness of this disease is strongly emphasized, with promotion of self-care and regular algorithms for breast examination. Occult breast cancer with axillary metastases is a rare entity characterized by the appeareance of metastatic lesions in axillary lymphnodes that point to the origin of the glandular breast tissue, but without the accompanying clinical, imaging or even histological confirmation of the focal point in the breast. There is a limited number of references in Croatian as well as in world literature which concerns this rare disease. During the observed period, a limited number of patients with confirmed entity of occult breast cancer with axillary metastases, are continously followed in General Hospital Dubrovnik. All the patients has all the necessary medical records related to the diagnosis, treatment and follow up. This paper presents the experiences in diagnosis and treatment using overall medical documentation of the patients with this entity during past 20 years in General Hospital Dubrovnik. All data was analyzed regarding the age of patients, possible family history, histological typs of the disease and the methods and results of the treatment including possible appeareance of local recurrence or disease dissemination, as well as the survival rate after initial diagnosis, depending on the undergoing therapeutic procedures. The paper also presents the role of the nurses in the treatment and care process and the monitoring of the patients.