The manufacturing industry represents the most important and the strongest promoter of a countries economy, including Croatia, and has a significant amount in the economy of Varaždin County. According to Nacional classification of activities (NKD 2007.) Croatia has 21 main activities which are marked with letters from A to U. The manufacturing industry is marked with the letter C and it includes 24 sub activities from c10 to c33. Traditionally Varaždin County has developed entrepreneurship, openness to investors and business with neighbouring countries, member countries of the European Union, as well as business with the whole world. In the structure of Varaždin County economy dominates the manufacturing industry with very strong trade, construction, transport and agriculture. The fact that in 2021. the manufacturing industry of Varaždin County took part with 50% of total income of the County and 49% of the total number of employees also speaks of the importance of Varaždin County manufacturing industry. Throughout the work selected indicators are analysed (number of entrepreneurs, number of employees and total income) of the manufacturing industry for 2019., 2020., and 2021., the environment (external and internal) of the manufacturing industry of Varaždin County is also analysed and through the application of strategic management tools, possible suggestions and guidelines for the further development of the manufacturing industry of Varaždin County were given.