Malaria is one of the most important acute and infectious diseases in human history. Malaria in humans is caused by six types of plasmia: Plasmodium falciparum, Plasmoduium Vivax, Plasmodium ovale, Plasmodium malarie and Plasmodium knowlesi. Most cases of malaria are caused by P. Vivax and P. falciparum, and the deaths are caused by P. falciparum. Malaria can be complicated and uncomplicated. The disease is transmitted by the bite of the infected mosquito female Anopheles. Malaria can also be transmitted by blood transfusion, injection of a contaminated needle or transplantation of the infected person's organs and can be transmitted during pregnancy from mother to child. The disease is endemic in 108 countries worldwide, tropical and subtropical. It first appeared on our territory in the 14 th century, 1320, when the Venetian Republic conducted recruitment of its soldiers in the area of malaria. Since then, malaria has been present in western Istria. It is believed that the reasons for the appearance of malaria on the peninsula were related to geological and climatic conditions in war devastation, the consequent degradation of fertile soil into pastures and wetlands and migrations of the population. According to a World Health Organisation report, a total of 106 countries were exposed to infection in 2011. A total of around 216 million cases of malaria occurred in 2010, of which 81% were recorded in the African region, in the southeastern Asia 13% and in the eastern Mediterranean region 5%. In general, nowadays it is important to find a way to prevent mosquito reproduction. Basic measures for the suppression of mosquitoes can be environmental management or implementation of physical, biological, mechanical and chemical measures. The approach that would pay off most is a combination of these measures in the suppression of mosquitoes. Malaria was eradicated in the Republic of Croatia in 1964 and today only imported cases are recorded, created in numerous endemic areas of malaria in the world. Until the imported cases are discovered and cured in due time, they pose a constant danger. The role of Bachelor of nursing in education is focused on prevention and then on interventions and holistic approach of patients. Prevention is important in passengers, children and pregnant women. Recommendations for the prevention of malaria in long-term travellers must be individualised.