Entrepreneurship of young people refers to entrepreneurs aged between 18 and 35 years. The social group of people up to 35 years of age is at a degree of maturity and preparedness for the world of work closer to a group of 25 to 30 years. Therefore it is more real for them to belong to category of young people. In a modern, highly variable world, entering the world of entrepreneurship is a very difficult and dynamic task. Young people in Croatia, in general, are more likely to decide to enter into entrepreneurship for essential reasons, while on the other hand young people in the Istrian region enter the entrepreneurship because of the high motivation and better conditions for the development of entrepreneurship in the region. The aim of this paper is to examine entrepreneurs operating in the area of Istria region and to conclude what they see as the greatest opportunities and challenges in Croatia and in the Istrian region. Part of the entrepreneurs who were questioned in this diploma decided to embark on developing their own business with infrastructure for entrepreneurship, while the others were either self-employed or previously in some form of infrastructure, and they are currently work independently. A common source of information for all the businesses was the internet. Although the young creators of their own jobs derive from the infrastructural program, they relied more on mentor information, and those in independent development on online sources and advice from accountant. As the biggest advantage of local businesses, they see the possibility of obtaining non-refundable funds from the city and the county, as well as a smaller market. Recognizing shortcomings are mutually different between entrepreneurs as a result of different job placement and dealing with different activities. Thus, most business owners, as disadvantages, point out those issues that are directly related to their business, and some of the biggest problems are the lack of awareness of the environment, the blame on initial errors, insufficient awareness of the importance of digital marketing, and some of them as the key issue see too much focus on tourism. Regarding the national level, the greatest challenges are to get the environment's favor because of age and to overcome the high costs associated with relatively high compulsory contributions. As in Croatia there are laws and opportunities for obtaining funds and many other help options, the situation is not as bad as it sometime seems. What the future will bring? It depends in which direction country economy will go. If we can bring back the faith of young people to stay in the country, they will be the holders of social and economic development. Actually, what they supposed to.