The main purpose of this thesis is to point out the important role of entrepreneurship in the development of local and regional self-government, and that it is necessary to continuously invest in the education of entrepreneurs themselves in order to bring added value to the area in which they operate. At the very beginning of the work, the concepts of entrepreneur and entrepreneurship are defined by the definitions of world authors, the historical development of entrepreneurship is explained, as well as the economic role and development of public administration, which can be observed through the connection with general economic, cultural and social development. Throughout history, public administration has been significantly involved in the lives of citizens, and generally plays an important role in the lives of all citizens. In its development, administration, both state administration and local and regional self-government, changed and played an important role in the functioning of communities. The paper also discusses the development of the public sector as a system whose common goal is to satisfy the interests and needs of citizens. The public sector appears as a feature that ensures the state performs its tasks in an efficient, transparent and accessible manner. There is a growing need to introduce entrepreneurship in the development of local and regional self-government. The issue of new ideas and the transformation of ideas into business ventures is a fundamental issue of entrepreneurship development. The results of the research tell us that there is still insufficient investment in the development of entrepreneurs and that it is necessary to develop entrepreneurship and entrepreneurs in the area of a certain local and regional self-government so that all residents of a certain area ultimately have benefits and a better standard of living.