When studying the history of the island Brač, exploring antique cults on its historic area plays an important role. The aim of this work is to show, clarify and to interpret cults known from other parts of the Roman world which overcame the island of Brač in the beginning of a new era. The foundation to reconstruct the religious understanding of the island consists of archeologic structure of the island, respectively its epigraphic monuments, cult reliefs and remains of a sacred architecture. Most of the attention is dedicated to the Roman God Herakles who, as the protector of stonemasons, facilitated everyday job at the stonepit and brought portion of success to the hard work. Other deity important to mention is Silvan whose monuments testify the roots of the cult who, after Roman arrival, survived the absolute alteration of way of living. Other cults, such as oriental, infiltrated the soil of Brač during the 3rd century. The work highlighted the importance of the "Škrip" as the greatest and the most significant place of the island during the Roman Empire in the 4th century after Christ.