Anesthesia and analgesia are routine procedures in surgery that are also applied to pigs. Especially pigs that are used in biomedical research for ethical reasons and a humane attitude towards the animal that contributes to the improvement of human life. Apart from them, attention is also focused on pigs as pets, whose owners have no problem spending extra money for better health care, which also includes painless surgical procedures. A doctor of veterinary medicine must be able to recognize the signs that point to painful conditions and discomfort felt by the animal and react appropriately in order to reduce and alleviate the pain. This topic may have marginal overtones, but only for the layman because experts have long known that humans and animals, primarily vertebrates, share very similar neuroanatomical structures related to the sensation of pain. That's why in every situation we have to be as considerate as possible towards the patient and enable him to have the procedure as painless as possible according to the rules of the profession. Of course, the situation is not the same in field conditions or in an equipped clinic that has the most modern technology and equipment, and we must be aware of the situation in which we work and what we have at our disposal in order to deliver the optimal medical service under the given circumstances.