Canine parvovirus causes high morbidity and mortality in dogs, particularly puppies between six weeks and six months old, though the disease also occurs in older dogs. Dogs are most commonly infected through contact with infected faeces. The virus enters the body through the nasal mucosa, multiplies in the lymphocytes of the oropharynx, and is transported by the blood to the crypts of the small intestine. In the small intestine, parvovirus infects the germinal epithelium of the intestinal crypts and causes its degradation, leading to the shortening of intestinal villi. Clinically, the disease can manifest as parvoviral enteritis and myocarditis. Symptoms of enteritis include vomiting, diarrhoea, anorexia, and dehydration. Death occurs as a result of sepsis or disseminated intravascular coagulation. Myocarditis typically presents as sudden death without prior signs and affects all puppies in the litter. The disease is diagnosed in practice using a rapid immunoenzymatic test or polymerase chain reaction. Treatment of parvoviral infection includes supportive and symptomatic therapy, which involves fluid and antimicrobial therapy, as well as antiemetics. Recent research examines the effectiveness of faecal transplantation, hyperimmune and convalescent sera, monoclonal antibodies, growth factors and antiviral drugs in treating this disease.