Systemic inflammatory response syndrome (SIRS) is a clinical manifestation of systemic inflammation induced by various causes. Some of the most common include sepsis, trauma, burns and neoplasia. This syndrome is often related to increased morbidity and mortality in animals. This research included ten dogs that developed signs of SIRS and that were admissioned at the Clinic for surgery, orthopedics and ophthalmology, because of trauma or they needed surgical intervention in the abdominal cavity. All the data was collected in the time period from August 14th 2013 until August 17th 2015. SIRS was diagnosed based on fulfillment of at least two out of four following criteria: hypo- or hyperthermia, tachycardia, tachypnea, leukocytosis or leukopenia or a left shift. The blood samples were collected from all ten dogs for hematological analysis, and from five dogs for serum biochemistry analysis. All of the dogs were re-evaluated clinically during hospitalization. We compared clinical, hematological and serum biochemistry data. This research showed that the most frequent SIRS parameter was leukocytosis, followed by tachypnea. However, there was no link found between certain SIRS parameter and a lethal outcome. Neither was there a link found between the number of occurring parameters and a lethal outcome. A much higher survival rate was observed in this research than in other researches. Considering variability of the SIRS criteria and its unreliability in dogs, further research ought to be conducted to determine diagnostically and prognostically relevant factors.