This final paper on the topic "Safety and Security in the Graphic Industry" will present the most important components of security in printing plants through several important units. The second part will be generally on the basics of safety and security at work. In the third part of the work, through a small historical presentation, the most important graphic machines and their development will be indicated in order to better understand the observed matter itself. Then the fourth and fifth parts focus on sources of danger, harm and effort and this will be presented through the three main elements of the production process, which are preparatory production, printing and graphic finishing. The penultimate part of this final work will be directed towards the solution of the problem itself, i.e. the solution of the problem, will deal with the issue of achieving safety through the above main elements of the production process. The last part describes personal protective equipment, evacuation plan, safety signs and first aid.