Burnout syndrome is recognized as an important issue due to its adverse effects on health and work behavior. It is associated with absenteeism, turnover, reduced productivity and efficiency, and employees' mental and physical health problems. Psychological climate is a construct that encompasses individual perceptions of important elements of the work environment. Climate perceptions are significantly linked to job satisfaction, work attitudes, psychological well-being, motivation, and work efficiency, which is why this study examined the contribution of psychological climate to the occurrence of workplace burnout. Additionally, we investigated whether remote work moderates the relationship between the social dimensions of psychological climate and burnout. The study included employees in the ICT sector (information and communication technology) in Croatia, where remote work is particularly prevalent. All dimensions of psychological climate (work role, work tasks, leadership, and work group) negatively correlate with burnout, but only perceptions of work tasks and work role were significant predictors of burnout. The contributions of task challenge, task diversity, task importance, autonomy in performing tasks, and role ambiguity and conflict in explaining burnout were identified. The moderating effect of the remote work on the relationship between work group perception and burnout was confirmed at all levels of the moderator, with the negative correlation between work group perception and burnout symptoms being greater for participants working more in the office. The study highlights practical implications for organizational practice, methodological limitations, and provides recommendations for future research.