Skepticism is a term that was developed in ancient Greece. Its basic assumption is doubt, but from this doubt developed an entire branch of philosophy - epistemology. The first part of the paper refers to the concept of skepticism, its development throughout history, the authors who contributed to it and the types of skepticism: Pyrrhonism demands that all conclusions need to be suspended because, in their viewpoint, it is impossible to assert that one fact is truer or more accurate than another. Academic skepticism, on the other hand, still leaves us with the possibility of drawing conclusions and says that no fact or knowledge is true. In addition to these ancient branches of skepticism, there are also skepticisms about certain areas of knowledge. Under specific skepticism we also consider rational or scientific skepticism, which presupposes doubt towards any forms of "knowledge" that is not confirmed by empirical evidence and the scientific method. Out of scientific skepticism has developed an entire movement that aims to subjugate the fringes of science to the scientific method, such as paranormal beliefs, pseudo-science and conspiracy theories. The second part of this paper deals with conspiracy theories. Conspiracy theories have been especially rampant during the COVID-19 pandemic, and therefore this time is crucially important in the study of conspiracies in order to show the advantages and disadvantages of such beliefs, and to educate the public on how to distinguish scientific theories from conspiracy theories. In the third part of the paper, which deals with the comparison of skeptics and conspiracy theorists, an analysis of the literature leads to the conclusion that conspiracy theories are the result of guillability, not rational skepticism, and that rational skepticism in people leads to the rejection of conspiracy theories.