Menopause is a natural time in a woman's life, not a disease. It is the result of reduced production of sex hormones in the ovaries and progesterone, estrogen and testosterone. The period in which most women enter menopause are between 45 and 55 years. A large number of women are most susceptible to heat waves and night sweats. The most effective way of treating these symptoms is hormone replacement therapy. Heat waves can be reduced even by 80% -90% of occurrence. Hormone Replacement Therapy (HNT) is the name for a group of drugs used in women with estrogen deficiency. Hormone replacement therapy is most commonly used in perimenopause and postmenopausal women. At least 2 to 3 years after menopause, hormone therapy should be initiated, as only then can the HNT's positive effect be expected for the symptoms of estrogen deficiency. Hormone replacement therapy carries certain risks. Risks that may occur depend on the age of the woman when she started to take the therapy, the type of preparation, the hormone dose, the route of intake and duration. There are four types of hormone replacement therapy and this is a concurrent hormone replacement therapy with estrogen and progesterone (progesterone protects against endometrial cancer), for women without hysterectomy, hormone replacement therapy with estrogen alone for women without a uterus because of hysterectomy, HNT with estrogen with additional testosterone use for the scarce women who were removed from both the janitor and the uterus. If removals are created for endometriosis, estrogen and progesterone are prescribed for preventing re-activation of endometriosis. Vaginal application of estrogen for women with symptom of dryness of the vagina, itching or painful sleepiness. The aim of this paper was to show the hormone therapy in menopause, ie the benefits and risks of its use.