prikaz prve stranice dokumenta Successful right atrial thrombus lysis with alteplase in a nine month old infant
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Successful right atrial thrombus lysis with alteplase in a nine month old infant
Signa vitae : journal for intesive care and emergency medicine, 8 (2013), 1; 59-61. urn:nbn:hr:184:820255
Lah Tomulić, Kristina; Frketa, Neven; Čače, Neven; Roganović, Jelena; Banac, Srđan; Tomulić, Vjekoslav; Gobić, David

Institucijski repozitorij: Repozitorij Medicinskog fakulteta u Rijeci

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Lah Tomulić, K., Frketa, N., Čače, N., Roganović, J., Banac, S., Tomulić, V. i Gobić, D. (2013). Successful right atrial thrombus lysis with alteplase in a nine month old infant. Signa vitae : journal for intesive care and emergency medicine, 8. (1), 59-61. Preuzeto s https://urn.nsk.hr/urn:nbn:hr:184:820255

Lah Tomulić, Kristina, et al. "Successful right atrial thrombus lysis with alteplase in a nine month old infant." Signa vitae : journal for intesive care and emergency medicine, vol. 8, br. 1, 2013, str. 59-61. https://urn.nsk.hr/urn:nbn:hr:184:820255

Lah Tomulić, Kristina, Neven Frketa, Neven Čače, Jelena Roganović, Srđan Banac, Vjekoslav Tomulić i David Gobić. "Successful right atrial thrombus lysis with alteplase in a nine month old infant." Signa vitae : journal for intesive care and emergency medicine 8, br. 1 (2013): 59-61. https://urn.nsk.hr/urn:nbn:hr:184:820255

Lah Tomulić, K., et al. (2013) 'Successful right atrial thrombus lysis with alteplase in a nine month old infant', Signa vitae : journal for intesive care and emergency medicine, 8(1), str. 59-61. Preuzeto s: https://urn.nsk.hr/urn:nbn:hr:184:820255 (Datum pristupa: 25.04.2024.)

Lah Tomulić K, Frketa N, Čače N, Roganović J, Banac S, Tomulić V, i sur.. Successful right atrial thrombus lysis with alteplase in a nine month old infant. Signa vitae : journal for intesive care and emergency medicine [Internet]. 01.04.2013. [pristupljeno 25.04.2024.];8(1):59-61. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:820255

K. Lah Tomulić, et al., "Successful right atrial thrombus lysis with alteplase in a nine month old infant", Signa vitae : journal for intesive care and emergency medicine, vol. 8, br. 1, str. 59-61, Travanj 2013. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:820255. [Citirano: 25.04.2024.]

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Podaci o radu
Naslov (engleski)Successful right atrial thrombus lysis with alteplase in a nine month old infant
AutorKristina Lah Tomulić
AutorNeven Frketa
AutorNeven Čače
AutorJelena Roganović
AutorSrđan Banac
AutorVjekoslav Tomulić
AutorDavid Gobić
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za internu medicinu)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za pedijatriju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Objective. To present the case of an infant with a catheter related atrial thrombus resolved with local instillation of alteplase. Clinical presentation. Echocardiography (ECHO) was performed in an infant with sepsis to estimate cardiac contractility, and a large mobile thrombus (28 x 8 mm) was detected in the right atrium. A left subclavian, double lumen, central venous line (CVL, 4 French, 8 cm), inserted 10 weeks previously, was left in place. Standard treatment with enoxaparine was commenced twice daily for 10 days at a dose of 1 mg/kg. Repeat ECHO showed no changes in thrombus size or mobility. Therefore, alteplase was administered into the distal catheter (1 mg in normal saline) at a dose of 110% of its priming volume. The dwelling time was 2 hours. Since no changes in thrombus size were observed, the same dose was given into the proximal catheter. ECHO performed 24 hours later showed a significant reduction in thrombus size. The third dose of alteplase was administered into the proximal catheter. ECHO showed complete dissolution of the right atrial thrombus. No bleeding was observed during and following therapy, and there were no signs of hemodynamic instability. The CVL was safely removed the same day and no endoluminal thrombus was seen. Conclusion. Local instillation of alteplase in three doses was a safe and effective approach to the management of a large catheter-related intraatrial thrombus. Systemic thrombolytic therapy, associated with an increased risk of bleeding, and open heart surgery were avoided.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeStručni rad - Stručni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaSigna vitae : journal for intesive care and emergency medicine
Brojčani podacivol. 8, br. 1, str. 59-61
p-ISSN1334-5605
e-ISSN1845-206X
URN:NBNurn:nbn:hr:184:820255
Datum objave publikacije2013-04-01
URL dokumentahttp://hrcak.srce.hr/108799
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2017-09-19 22:01:59