prikaz prve stranice dokumenta Diagnostic accuracy of heart fatty acid binding protein (H-FABP) and glycogen phosphorylase isoenzyme BB (GPBB) in diagnosis of acute myocardial infarction in patients with acute coronary syndrome
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Diagnostic accuracy of heart fatty acid binding protein (H-FABP) and glycogen phosphorylase isoenzyme BB (GPBB) in diagnosis of acute myocardial infarction in patients with acute coronary syndrome
Biochemia medica : Biochemia medica, 22 (2012), 2; 225-236. urn:nbn:hr:184:856636
Čubranić, Zlatko; Madžar, Željko; Matijević, Sanja; Dvornik, Štefica; Fišić, Elizabeta; Tomulić, Vjekoslav; Kunišek, Juraj; Laškarin, Gordana; Kardum, Igor; Zaputović, Luka

Institucijski repozitorij: Repozitorij Medicinskog fakulteta u Rijeci

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Čubranić, Z., Madžar, Ž., Matijević, S., Dvornik, Š., Fišić, E., Tomulić, V. ... Zaputović, L. (2012). Diagnostic accuracy of heart fatty acid binding protein (H-FABP) and glycogen phosphorylase isoenzyme BB (GPBB) in diagnosis of acute myocardial infarction in patients with acute coronary syndrome. Biochemia medica : Biochemia medica, 22. (2), 225-236. Preuzeto s https://urn.nsk.hr/urn:nbn:hr:184:856636

Čubranić, Zlatko, et al. "Diagnostic accuracy of heart fatty acid binding protein (H-FABP) and glycogen phosphorylase isoenzyme BB (GPBB) in diagnosis of acute myocardial infarction in patients with acute coronary syndrome." Biochemia medica : Biochemia medica, vol. 22, br. 2, 2012, str. 225-236. https://urn.nsk.hr/urn:nbn:hr:184:856636

Čubranić, Zlatko, Željko Madžar, Sanja Matijević, Štefica Dvornik, Elizabeta Fišić, Vjekoslav Tomulić, Juraj Kunišek, Gordana Laškarin, Igor Kardum i Luka Zaputović. "Diagnostic accuracy of heart fatty acid binding protein (H-FABP) and glycogen phosphorylase isoenzyme BB (GPBB) in diagnosis of acute myocardial infarction in patients with acute coronary syndrome." Biochemia medica : Biochemia medica 22, br. 2 (2012): 225-236. https://urn.nsk.hr/urn:nbn:hr:184:856636

Čubranić, Z., et al. (2012) 'Diagnostic accuracy of heart fatty acid binding protein (H-FABP) and glycogen phosphorylase isoenzyme BB (GPBB) in diagnosis of acute myocardial infarction in patients with acute coronary syndrome', Biochemia medica : Biochemia medica, 22(2), str. 225-236. Preuzeto s: https://urn.nsk.hr/urn:nbn:hr:184:856636 (Datum pristupa: 26.12.2024.)

Čubranić Z, Madžar Ž, Matijević S, Dvornik Š, Fišić E, Tomulić V, i sur.. Diagnostic accuracy of heart fatty acid binding protein (H-FABP) and glycogen phosphorylase isoenzyme BB (GPBB) in diagnosis of acute myocardial infarction in patients with acute coronary syndrome. Biochemia medica : Biochemia medica [Internet]. 15.06.2012. [pristupljeno 26.12.2024.];22(2):225-236. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:856636

Z. Čubranić, et al., "Diagnostic accuracy of heart fatty acid binding protein (H-FABP) and glycogen phosphorylase isoenzyme BB (GPBB) in diagnosis of acute myocardial infarction in patients with acute coronary syndrome", Biochemia medica : Biochemia medica, vol. 22, br. 2, str. 225-236, Lipanj 2012. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:856636. [Citirano: 26.12.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:856636
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Naslov (engleski)Diagnostic accuracy of heart fatty acid binding protein (H-FABP) and glycogen phosphorylase isoenzyme BB (GPBB) in diagnosis of acute myocardial infarction in patients with acute coronary syndrome
AutorZlatko Čubranić
AutorŽeljko Madžar
AutorSanja Matijević
AutorŠtefica Dvornik
AutorElizabeta Fišić
AutorVjekoslav Tomulić
AutorJuraj Kunišek
AutorGordana Laškarin
AutorIgor Kardum
AutorLuka Zaputović
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za internu medicinu)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za kliničko-laboratorijsku dijagnostiku)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Introduction: This study aimed to assess whether heart fatty acid-binding protein (H-FABP) and glycogen phosphorylase isoenzyme BB (GPBB) could be used for the accurate diagnosis of acute myocardial infarction (AMI) in acute coronary syndrome (ACS) patients. Materials and methods: The study included 108 ACS patients admitted to a coronary unit within 3 h after chest pain onset. AMI was distinguished from unstable angina (UA) using a classical cardiac troponin I (cTnI) assay. H-FABP and GPBB were measured by ELISA on admission (0 h) and at 3, 6, 12, and 24 h after admission; their accuracy to diagnose AMI was assessed using statistical methods. Results: From 92 patients with ACS; 71 had AMI. H-FABP and GPBB had higher peak value after 3 h from admission than cTnI (P = 0.001). Both markers normalized at 24 h. The area under the receiver operating characteristic curves was significantly greater for both markers in AMI patients than in UA patients at all time points tested, including admission (P < 0.001). At admission, the H-FABP (37%) and GPBB (40%) sensitivities were relatively low. They increased at 3 and 6 h after admission for both markers and decreased again after 24 h. It was 40% for H-FABP and approximately 2-times lower for GPBB (P < 0.01). In AMI patients, both biomarkers had similar specificities, positive- and negative-predictive values, positive and negative likelihood ratios, and risk ratios for AIM. Conclusion: H-FABP and GPBB can contribute to early AMI diagnosis and can distinguish AMI from UA.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaBiochemia medica : Biochemia medica
Brojčani podacivol. 22, br. 2, str. 225-236
p-ISSN1330-0962
URN:NBNurn:nbn:hr:184:856636
Datum objave publikacije2012-06-15
URL dokumentahttp://hrcak.srce.hr/83227
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2017-09-19 22:07:05