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Bone Turnover in Homozygous ß2-Microglobulin Knock-Out Mice Does not Differ from That of Their Heterozygous Littermates
European Journal of Clinical Chemistry and Cinical Biochemistry, 33 (1995); 915-918. https://doi.org/10.1515/cclm.1995.33.12.915
Marušić, Ana; Katavić, Vedran; Štimac, Dinko; Kušec, Vesna; Jonjić, Stipan

Institucijski repozitorij: Repozitorij Medicinskog fakulteta u Rijeci

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Marušić, A., Katavić, V., Štimac, D., Kušec, V. i Jonjić, S. (1995). Bone Turnover in Homozygous ß2-Microglobulin Knock-Out Mice Does not Differ from That of Their Heterozygous Littermates. European Journal of Clinical Chemistry and Cinical Biochemistry, 33., 915-918. doi: 10.1515/cclm.1995.33.12.915

Marušić, Ana, et al. "Bone Turnover in Homozygous ß2-Microglobulin Knock-Out Mice Does not Differ from That of Their Heterozygous Littermates." European Journal of Clinical Chemistry and Cinical Biochemistry, vol. 33, 1995, str. 915-918. https://doi.org/10.1515/cclm.1995.33.12.915

Marušić, Ana, Vedran Katavić, Dinko Štimac, Vesna Kušec i Stipan Jonjić. "Bone Turnover in Homozygous ß2-Microglobulin Knock-Out Mice Does not Differ from That of Their Heterozygous Littermates." European Journal of Clinical Chemistry and Cinical Biochemistry 33 (1995): 915-918. https://doi.org/10.1515/cclm.1995.33.12.915

Marušić, A., et al. (1995) 'Bone Turnover in Homozygous ß2-Microglobulin Knock-Out Mice Does not Differ from That of Their Heterozygous Littermates', European Journal of Clinical Chemistry and Cinical Biochemistry, 33, str. 915-918. doi: 10.1515/cclm.1995.33.12.915

Marušić A, Katavić V, Štimac D, Kušec V, Jonjić S. Bone Turnover in Homozygous ß2-Microglobulin Knock-Out Mice Does not Differ from That of Their Heterozygous Littermates. European Journal of Clinical Chemistry and Cinical Biochemistry [Internet]. 1995. [pristupljeno 24.12.2024.];33:915-918. doi: 10.1515/cclm.1995.33.12.915

A. Marušić, V. Katavić, D. Štimac, V. Kušec i S. Jonjić, "Bone Turnover in Homozygous ß2-Microglobulin Knock-Out Mice Does not Differ from That of Their Heterozygous Littermates", European Journal of Clinical Chemistry and Cinical Biochemistry, vol. 33, str. 915-918, 1995. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:201372. [Citirano: 24.12.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:201372
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Naslov (engleski)Bone Turnover in Homozygous ß2-Microglobulin Knock-Out Mice Does not Differ from That of Their Heterozygous Littermates
AutorAna Marušić
AutorVedran Katavić
AutorDinko Štimac
AutorVesna Kušec
AutorStipan Jonjić
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Sažetak (engleski)
Beta2-microglobulin is a constituent of the class I major histocompatibility complex (MHC) molecule and crucial for its normal function in cell recognition.It has also been isolated from bone and shown to regulate bone metabolism and to be altered in various bone diseases.In order to further investigate teh role of the immune system in bone metabolism, we studied basic properties of bone physiology in beta2-microglobulin-deficient mice created by the tehnique of gene knock-out.Ten week-old male offspring homozygous (non-functional class I MHC molecule) or heterozygous (functional class I MHC molecule) for beta2-microglobulin knock-out gene did not differ in the following measures of bone turnover: femur lenght, dry and ash weight and calcium content, serum calcium concentration and alkaline phosphatase activity, total vertebral tissue area, trabecular bone volume, osteid surface, osteoclast surface and mineral apposition rate.These data indicate that the bone turnover in beta2-microglobulin-deficient mice is appropriate for the stage of their skeletal maturation.
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaEuropean Journal of Clinical Chemistry and Cinical Biochemistry
Brojčani podacivol. 33, str. 915-918
p-ISSN0939-4974
DOIhttps://doi.org/10.1515/cclm.1995.33.12.915
URN:NBNurn:nbn:hr:184:201372
Datum objave publikacije1995
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2018-11-22 21:15:07