prikaz prve stranice dokumenta Association between PLA2G6 gene polymorphism for calcium-independent phospholipase A2 and nicotine dependence among males with schizophrenia
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Association between PLA2G6 gene polymorphism for calcium-independent phospholipase A2 and nicotine dependence among males with schizophrenia
Prostaglandins, Leukotrienes and Essential Fatty Acids, 148 (2019); 9-15. https://doi.org/10.1016/j.plefa.2019.07.005
Nadalin, Sergej; Rebić, Jelena; Šendula Jengić, Vesna; Peitl, Vjekoslav; Karlović, Dalibor; Buretić-Tomljanović, Alena

Institucijski repozitorij: Repozitorij Medicinskog fakulteta u Rijeci

Citirajte ovaj rad

Nadalin, S., Rebić, J., Šendula Jengić, V., Peitl, V., Karlović, D. i Buretić Tomljanović, A. (2019). Association between PLA2G6 gene polymorphism for calcium-independent phospholipase A2 and nicotine dependence among males with schizophrenia. Prostaglandins, Leukotrienes and Essential Fatty Acids, 148., 9-15. doi: 10.1016/j.plefa.2019.07.005

Nadalin, Sergej, et al. "Association between PLA2G6 gene polymorphism for calcium-independent phospholipase A2 and nicotine dependence among males with schizophrenia." Prostaglandins, Leukotrienes and Essential Fatty Acids, vol. 148, 2019, str. 9-15. https://doi.org/10.1016/j.plefa.2019.07.005

Nadalin, Sergej, Jelena Rebić, Vesna Šendula Jengić, Vjekoslav Peitl, Dalibor Karlović i Alena Buretić Tomljanović. "Association between PLA2G6 gene polymorphism for calcium-independent phospholipase A2 and nicotine dependence among males with schizophrenia." Prostaglandins, Leukotrienes and Essential Fatty Acids 148 (2019): 9-15. https://doi.org/10.1016/j.plefa.2019.07.005

Nadalin, S., et al. (2019) 'Association between PLA2G6 gene polymorphism for calcium-independent phospholipase A2 and nicotine dependence among males with schizophrenia', Prostaglandins, Leukotrienes and Essential Fatty Acids, 148, str. 9-15. doi: 10.1016/j.plefa.2019.07.005

Nadalin S, Rebić J, Šendula Jengić V, Peitl V, Karlović D, Buretić Tomljanović A. Association between PLA2G6 gene polymorphism for calcium-independent phospholipase A2 and nicotine dependence among males with schizophrenia. Prostaglandins, Leukotrienes and Essential Fatty Acids [Internet]. 2019. [pristupljeno 01.05.2024.];148:9-15. doi: 10.1016/j.plefa.2019.07.005

S. Nadalin, J. Rebić, V. Šendula Jengić, V. Peitl, D. Karlović i A. Buretić Tomljanović, "Association between PLA2G6 gene polymorphism for calcium-independent phospholipase A2 and nicotine dependence among males with schizophrenia", Prostaglandins, Leukotrienes and Essential Fatty Acids, vol. 148, str. 9-15, 2019. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:605890. [Citirano: 01.05.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:605890
Podaci o radu
Naslov (engleski)Association between PLA2G6 gene polymorphism for calcium-independent phospholipase A2 and nicotine dependence among males with schizophrenia
AutorSergej Nadalin
AutorJelena Rebić
AutorVesna Šendula Jengić
AutorVjekoslav Peitl
MBZ: 361852
AutorDalibor Karlović
MBZ: 251183
AutorAlena Buretić-Tomljanović
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za medicinsku biologiju i genetiku)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za psihijatriju i psihološku medicinu)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Genetika, genomika i proteomika čovjeka
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Psihijatrija
Sažetak (engleski)
We investigated the relationship between the rs10798059 (BanI) and rs4375 polymorphisms in the phospholipase A2 (PLA2)G4A and PLA2G6 genes and the risk of nicotine dependence in 263 Croatian patients with schizophrenia. We also examined whether interactions between these polymorphisms and smoking contributed to schizophrenia onset and Positive and Negative Syndrome Scale (PANSS) psychopathology. We found no significant differences in the distribution of PLA2G4A genotypes and alleles according to smoking status, and no effect of the PLA2G4A genotype-smoking interaction on disease onset or PANSS. The PLA2G6-TT homozygous genotype was significantly overrepresented in male smokers compared to nonsmokers (34.7% vs. 17.1%, p < 0.05). These patients had similar to 2.6-fold higher risk of becoming smokers than males with heterozygous PLA2G6-CT and homozygous PLA2G6-CC genotypes. In addition, male smokers without the PLA2G6-C allele (PLA2G6-TT homozygous) experienced earlier onset than nonsmoking homozygous PLA2G6-TT males. Thus, the PLA2G6 polymorphism affected the risk of nicotine dependence in male patients and the PLA2G6 genotype smoking interaction was linked to the age of disease onset.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaProstaglandins, Leukotrienes and Essential Fatty Acids
Brojčani podacivol. 148, str. 9-15
p-ISSN0952-3278
DOIhttps://doi.org/10.1016/j.plefa.2019.07.005
URN:NBNurn:nbn:hr:184:605890
Datum objave publikacije2019
URL dokumentahttp://bib.irb.hr/1058720
Vrsta resursaTekst
Prava pristupaInstitucijski pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2022-02-08 12:26:51