prikaz prve stranice dokumenta Subclinical Autoimmune Thyroid Dysfunction in Infertile Euthyroid Patients: The Risk of Spontaneous Abortion
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Subclinical Autoimmune Thyroid Dysfunction in Infertile Euthyroid Patients: The Risk of Spontaneous Abortion
Journal of reproductive medicine, 65 (2020), 5-6; 169-174. urn:nbn:hr:184:243994
Petretić Majnarić, Silvana; Smiljan Severinski, Neda; Mrakovčić Šutić, Ines; Kustić, Domagoj; Blažević, Marina; Majnarić, Tea

Institucijski repozitorij: Repozitorij Medicinskog fakulteta u Rijeci

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Petretić Majnarić, S., Smiljan Severinski, N., Mrakovčić Šutić, I., Kustić, D., Blažević, M. i Majnarić, T. (2020). Subclinical Autoimmune Thyroid Dysfunction in Infertile Euthyroid Patients: The Risk of Spontaneous Abortion. Journal of reproductive medicine, 65. (5-6), 169-174. Preuzeto s https://urn.nsk.hr/urn:nbn:hr:184:243994

Petretić Majnarić, Silvana, et al. "Subclinical Autoimmune Thyroid Dysfunction in Infertile Euthyroid Patients: The Risk of Spontaneous Abortion." Journal of reproductive medicine, vol. 65, br. 5-6, 2020, str. 169-174. https://urn.nsk.hr/urn:nbn:hr:184:243994

Petretić Majnarić, Silvana, Neda Smiljan Severinski, Ines Mrakovčić Šutić, Domagoj Kustić, Marina Blažević i Tea Majnarić. "Subclinical Autoimmune Thyroid Dysfunction in Infertile Euthyroid Patients: The Risk of Spontaneous Abortion." Journal of reproductive medicine 65, br. 5-6 (2020): 169-174. https://urn.nsk.hr/urn:nbn:hr:184:243994

Petretić Majnarić, S., et al. (2020) 'Subclinical Autoimmune Thyroid Dysfunction in Infertile Euthyroid Patients: The Risk of Spontaneous Abortion', Journal of reproductive medicine, 65(5-6), str. 169-174. Preuzeto s: https://urn.nsk.hr/urn:nbn:hr:184:243994 (Datum pristupa: 13.05.2024.)

Petretić Majnarić S, Smiljan Severinski N, Mrakovčić Šutić I, Kustić D, Blažević M, Majnarić T. Subclinical Autoimmune Thyroid Dysfunction in Infertile Euthyroid Patients: The Risk of Spontaneous Abortion. Journal of reproductive medicine [Internet]. 2020. [pristupljeno 13.05.2024.];65(5-6):169-174. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:243994

S. Petretić Majnarić, N. Smiljan Severinski, I. Mrakovčić Šutić, D. Kustić, M. Blažević i T. Majnarić, "Subclinical Autoimmune Thyroid Dysfunction in Infertile Euthyroid Patients: The Risk of Spontaneous Abortion", Journal of reproductive medicine, vol. 65, br. 5-6, str. 169-174, 2020. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:243994. [Citirano: 13.05.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:243994
Podaci o radu
Naslov (engleski)Subclinical Autoimmune Thyroid Dysfunction in Infertile Euthyroid Patients: The Risk of Spontaneous Abortion
AutorSilvana Petretić Majnarić
AutorNeda Smiljan Severinski
AutorInes Mrakovčić Šutić
AutorDomagoj Kustić
MBZ: 384580
AutorMarina Blažević
AutorTea Majnarić
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za fiziologiju, imunologiju i patofiziologiju)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za ginekologiju i opstetriciju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
OBJECTIVE: To investigate whether in vitro fertilization (IVF) procedures in patients with autoimmune thyroid disorder increase the likelihood of conception and delivery. STUDY DESIGN: The study included 125 patients (N=241 with male factor cases included) who were treated for infertility at the tertiary center between 2009 and 2015, either conservatively or by IVF. In all the participants, thyroid function was assessed by measuring serum concentrations of thyroid- stimulating hormone, free thyroxine, and free triiodothyronine, whereas thyroid autoimmunity was assessed by measuring thyroid peroxidase antibodies and thyroglobulin antibodies (TgAb) in the serum samples, and by thyroid ultrasound examinations. The reproductive outcomes were compared between the infertile patients with autoimmune thyroid disorder and patients with normal hormone levels, negative thyroid antibody tests, and normal ultrasound findings. RESULTS: In the group of patients with autoimmune thyroid disorder who were treated by IVF, significantly more women conceived. Also, significantly more women in this group had spontaneous abortions as compared to the women with euthyroid (p=0.039). The number of births per woman did not differ significantly between the groups. The percentage of births (birth per patient) was similar and without significant statistical difference. Similar results were observed in patients with autoimmune thyroid disorders and combined infertility (female- male). CONCLUSION: IVF procedures significantly increase the likelihood of conception in patients with subclinical autoimmune thyroid disorder, but not the likelihood of delivery. Despite the euthyroid status as a result of levothyroxine replacement, the risk of spontaneous abortion was increased in patients with autoimmune thyroid disorder, regardless of the type of infertility treatment (conservative or IVF).
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaJournal of reproductive medicine
Brojčani podacivol. 65, br. 5-6, str. 169-174
p-ISSN0024-7758
URN:NBNurn:nbn:hr:184:243994
Datum objave publikacije2020
URL dokumentahttp://bib.irb.hr/1071270
Vrsta resursaTekst
Prava pristupaZatvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2022-03-09 15:16:09