prikaz prve stranice dokumenta Significant liver fibrosis, as assessed by fibroscan, is independently associated with chronic vascular complications of type 2 diabetes: A multicenter study
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Significant liver fibrosis, as assessed by fibroscan, is independently associated with chronic vascular complications of type 2 diabetes: A multicenter study
Diabetes Research and Clinical Practice, 177 (2021); 108884. https://doi.org/10.1016/j.diabres.2021.108884
Mikolašević, Ivana; Rahelić, Dario; Turk Wensween, Tamara; Ružić, Alen; Domislović, Viktor; Hauser, Goran; Matić, T.; Radić-Krišto, Delfa; Krznarić, Z.; Radić, M.; Filipec Kanižaj, Tajana; Martinović, M.; Jerkić, H.; Medjimurec, M.; Targher, G. Više autora...

Institucijski repozitorij: Repozitorij Medicinskog fakulteta u Rijeci

Citirajte ovaj rad

Mikolašević, I., Rahelić, D., Turk Wensween, T., Ružić, A., Domislović, V., Hauser, G. ... Targher, G. (2021). Significant liver fibrosis, as assessed by fibroscan, is independently associated with chronic vascular complications of type 2 diabetes: A multicenter study. Diabetes Research and Clinical Practice, 177.. doi: 10.1016/j.diabres.2021.108884

Mikolašević, Ivana, et al. "Significant liver fibrosis, as assessed by fibroscan, is independently associated with chronic vascular complications of type 2 diabetes: A multicenter study." Diabetes Research and Clinical Practice, vol. 177, 2021. https://doi.org/10.1016/j.diabres.2021.108884

Mikolašević, Ivana, Dario Rahelić, Tamara Turk Wensween, Alen Ružić, Viktor Domislović, Goran Hauser, T. Matić, et al. "Significant liver fibrosis, as assessed by fibroscan, is independently associated with chronic vascular complications of type 2 diabetes: A multicenter study." Diabetes Research and Clinical Practice 177 (2021). https://doi.org/10.1016/j.diabres.2021.108884

Mikolašević, I., et al. (2021) 'Significant liver fibrosis, as assessed by fibroscan, is independently associated with chronic vascular complications of type 2 diabetes: A multicenter study', Diabetes Research and Clinical Practice, 177. doi: 10.1016/j.diabres.2021.108884

Mikolašević I, Rahelić D, Turk Wensween T, Ružić A, Domislović V, Hauser G, i sur.. Significant liver fibrosis, as assessed by fibroscan, is independently associated with chronic vascular complications of type 2 diabetes: A multicenter study. Diabetes Research and Clinical Practice [Internet]. 07.2021. [pristupljeno 21.05.2024.];177. doi: 10.1016/j.diabres.2021.108884

I. Mikolašević, et al., "Significant liver fibrosis, as assessed by fibroscan, is independently associated with chronic vascular complications of type 2 diabetes: A multicenter study", Diabetes Research and Clinical Practice, vol. 177, Srpanj 2021. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:583907. [Citirano: 21.05.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:583907
Podaci o radu
Naslov (engleski)Significant liver fibrosis, as assessed by fibroscan, is independently associated with chronic vascular complications of type 2 diabetes: A multicenter study
AutorIvana Mikolašević
AutorDario Rahelić
AutorTamara Turk Wensween
AutorAlen Ružić
AutorViktor Domislović
AutorGoran Hauser
AutorT. Matić
AutorDelfa Radić-Krišto
AutorZ. Krznarić
AutorM. Radić
AutorTajana Filipec Kanižaj
AutorM. Martinović
AutorH. Jerkić
AutorM. Medjimurec
AutorG. Targher
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za internu medicinu)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Aims The aim of this study was to investigate whether controlled attenuation parameter (CAP) and liver stiffness measurement (LSM), as assessed by vibration-controlled transient elastography (VCTE), are associated with chronic vascular complications of diabetes mellitus type 2 (T2DM). Methods We studied 442 outpatients with established T2DM, and who underwent VCTE and extensive assessment of chronic vascular complications of diabetes. Results A quarter of analyzed patients had a previous history of myocardial infarction and/or ischemic stroke, and about half of them had at least one microvascular complication (chronic kidney disease (CKD), retinopathy or polyneuropathy). The prevalence of liver steatosis (i.e., CAP ≥ 238 dB/m) and significant liver fibrosis (i.e., LSM ≥ 7.0/6.2 kPa) was 84.2% and 46.6%, respectively. Significant liver fibrosis was associated with an increased likelihood of having myocardial infarction (adjusted-odds ratio 6.61, 95%CI 1.66– 37.4), peripheral polyneuropathy (adjusted-OR 4.55, 95%CI 1.25–16.6), CKD (adjusted-OR 4.54, 95%CI 1.24–16.6) or retinopathy (adjusted-OR 1.81, 95%CI 1.62–1.97), independently of cardiometabolic risk factors, diabetes-related variables, and other potential confounders. Liver steatosis was not independently associated with any macro-/microvascular diabetic complications. Conclusions Significant liver fibrosis is strongly associated with the presence of macro-/microvascular complications in patients with T2DM. These results offer a new perspective on the follow-up of people with T2DM.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaDiabetes Research and Clinical Practice
Brojčani podacivol. 177, 108884
p-ISSN0168-8227
DOIhttps://doi.org/10.1016/j.diabres.2021.108884
URN:NBNurn:nbn:hr:184:583907
Datum objave publikacije2021-07
URL dokumentahttps://linkinghub.elsevier.com/retrieve/pii/S0168822721002448
Vrsta resursaTekst
Prava pristupaInstitucijski pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2023-02-02 09:27:37