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The Association between the Firmicutes/Bacteroidetes Ratio and Body Mass among European Population with the Highest Proportion of Adults with Obesity: An Observational Follow-Up Study from Croatia
Biomedicines, 12 (2024), 10; 2263. https://doi.org/10.3390/biomedicines12102263
Karačić, Andrija; Renko, Ira; Krznarić, Željko; Klobučar, Sanja; Liberati Pršo, Ana-Marija

Institucijski repozitorij: Repozitorij Medicinskog fakulteta u Rijeci

Citirajte ovaj rad

Karačić, A., Renko, I., Krznarić, Ž., Klobučar, S. i Liberati Pršo, A. M. (2024). The Association between the Firmicutes/Bacteroidetes Ratio and Body Mass among European Population with the Highest Proportion of Adults with Obesity: An Observational Follow-Up Study from Croatia. Biomedicines, 12. (10). doi: 10.3390/biomedicines12102263

Karačić, Andrija, et al. "The Association between the Firmicutes/Bacteroidetes Ratio and Body Mass among European Population with the Highest Proportion of Adults with Obesity: An Observational Follow-Up Study from Croatia." Biomedicines, vol. 12, br. 10, 2024. https://doi.org/10.3390/biomedicines12102263

Karačić, Andrija, Ira Renko, Željko Krznarić, Sanja Klobučar i Ana Marija Liberati Pršo. "The Association between the Firmicutes/Bacteroidetes Ratio and Body Mass among European Population with the Highest Proportion of Adults with Obesity: An Observational Follow-Up Study from Croatia." Biomedicines 12, br. 10 (2024). https://doi.org/10.3390/biomedicines12102263

Karačić, A., et al. (2024) 'The Association between the Firmicutes/Bacteroidetes Ratio and Body Mass among European Population with the Highest Proportion of Adults with Obesity: An Observational Follow-Up Study from Croatia', Biomedicines, 12(10). doi: 10.3390/biomedicines12102263

Karačić A, Renko I, Krznarić Ž, Klobučar S, Liberati Pršo AM. The Association between the Firmicutes/Bacteroidetes Ratio and Body Mass among European Population with the Highest Proportion of Adults with Obesity: An Observational Follow-Up Study from Croatia. Biomedicines [Internet]. 04.10.2024. [pristupljeno 23.11.2024.];12(10). doi: 10.3390/biomedicines12102263

A. Karačić, I. Renko, Ž. Krznarić, S. Klobučar i A. M. Liberati Pršo, "The Association between the Firmicutes/Bacteroidetes Ratio and Body Mass among European Population with the Highest Proportion of Adults with Obesity: An Observational Follow-Up Study from Croatia", Biomedicines, vol. 12, br. 10, Listopad 2024. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:748983. [Citirano: 23.11.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:748983
Podaci o radu
Naslov (engleski)The Association between the Firmicutes/Bacteroidetes Ratio and Body Mass among European Population with the Highest Proportion of Adults with Obesity: An Observational Follow-Up Study from Croatia
AutorAndrija Karačić
AutorIra Renko
AutorŽeljko Krznarić
AutorSanja Klobučar
AutorAna-Marija Liberati Pršo
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za internu medicinu)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Background/Objectives: The phyla Firmicutes and Bacteroidetes are the main constituents of the gut microbiota. An imbalance in the gut microbiota is a sign of dysbiosis, and the Firmicutes-to-Bacteroidetes ratio has been proposed to be a marker of it, especially in the context of obesity. Since Croatia is the country with one of the highest obesity rates in Europe, a pilot observational study was conducted. The aim of the study was to investigate the validity of this potential biomarker in a methodological study using sample processing, DNA sequence analysis and characterization of recruited participants, including various health factors. Methods: A study involving Croatian population was conducted. Participants age, body weight, gender, health history and lifestyle factors were recorded. Gut microbiota composition was analyzed using 16S rRNA sequencing. The F/B ratio was calculated and evaluated in the context of health factors. Statistical analysis was performed to detect the possible association of F/B ratio and excess body weight (kg) and possible impact of certain lifestyle factors. Results: No association between the F/B ratio and excess body weight (kg) was found. Excess body weight was significantly associated with higher age, male gender, and history of appendectomy. No significant health predictors of the F/B ratio were found, but weight gain was positively associated with a higher average F/B ratio. Conclusions: Although this study could not confirm the predictive value of the F/B ratio or any other phyla-related biomarker for excess body weight in the study population, it demonstrated interesting insights into the obesity-associated gut microbiota.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaBiomedicines
Brojčani podacivol. 12, br. 10, 2263
e-ISSN2227-9059
DOIhttps://doi.org/10.3390/biomedicines12102263
URN:NBNurn:nbn:hr:184:748983
Datum objave publikacije2024-10-04
URL dokumentahttps://www.mdpi.com/2227-9059/12/10/2263
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2024-10-07 10:02:15