prikaz prve stranice dokumenta The influence of therapeutic hypothermia on the outcomes of cardiac arrest survivors: a retrospective cohort study
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The influence of therapeutic hypothermia on the outcomes of cardiac arrest survivors: a retrospective cohort study
Croatian Medical Journal, 61 (2020), 1; 40-48. https://doi.org/10.3325/cmj.2020.61.40
Pavlov, Marin; Babić, Zdravko; Đuzel, Ana; Crljenko, Krešimir; Nedić, Mislav; Delić Brkljačić, Diana

Institucijski repozitorij: Dr Med - digitalni repozitorij Medicinskog fakulteta Sveučilišta u Zagrebu

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Pavlov, M., Babić, Z., Đuzel, A., Crljenko, K., Nedić, M. i Delić Brkljačić, D. (2020). The influence of therapeutic hypothermia on the outcomes of cardiac arrest survivors: a retrospective cohort study. Croatian Medical Journal, 61. (1), 40-48. doi: 10.3325/cmj.2020.61.40

Pavlov, Marin, et al. "The influence of therapeutic hypothermia on the outcomes of cardiac arrest survivors: a retrospective cohort study." Croatian Medical Journal, vol. 61, br. 1, 2020, str. 40-48. https://doi.org/10.3325/cmj.2020.61.40

Pavlov, Marin, Zdravko Babić, Ana Đuzel, Krešimir Crljenko, Mislav Nedić i Diana Delić Brkljačić. "The influence of therapeutic hypothermia on the outcomes of cardiac arrest survivors: a retrospective cohort study." Croatian Medical Journal 61, br. 1 (2020): 40-48. https://doi.org/10.3325/cmj.2020.61.40

Pavlov, M., et al. (2020) 'The influence of therapeutic hypothermia on the outcomes of cardiac arrest survivors: a retrospective cohort study', Croatian Medical Journal, 61(1), str. 40-48. doi: 10.3325/cmj.2020.61.40

Pavlov M, Babić Z, Đuzel A, Crljenko K, Nedić M, Delić Brkljačić D. The influence of therapeutic hypothermia on the outcomes of cardiac arrest survivors: a retrospective cohort study. Croatian Medical Journal [Internet]. 29.02.2020. [pristupljeno 23.11.2024.];61(1):40-48. doi: 10.3325/cmj.2020.61.40

M. Pavlov, Z. Babić, A. Đuzel, K. Crljenko, M. Nedić i D. Delić Brkljačić, "The influence of therapeutic hypothermia on the outcomes of cardiac arrest survivors: a retrospective cohort study", Croatian Medical Journal, vol. 61, br. 1, str. 40-48, Veljača 2020. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:017640. [Citirano: 23.11.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:017640
Podaci o radu
Naslov (engleski)The influence of therapeutic hypothermia on the outcomes of cardiac arrest survivors: a retrospective cohort study
AutorMarin Pavlov
AutorZdravko Babić
AutorAna Đuzel
AutorKrešimir Crljenko
AutorMislav Nedić
AutorDiana Delić Brkljačić
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INTERNU MEDICINU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Aim: To determine whether therapeutic hypothermia (TH) improves survival and neurological outcomes in out-of-hospital cardiac arrest (OHCA) survivors. ----- Methods: This retrospective cohort study enrolled patients treated for OHCA with a return of spontaneous circulation admitted to the Cardiac Intensive Care Unit from October 2000 until March 2019. Data were collected from medical archives. Propensity score matching was used. The primary endpoint was death during hospital stay and secondary endpoint was cerebral performance category (CPC) score at discharge. ----- Results: Out of 152 patients included in the study, 58 (38.7%) underwent TH treatment. After matching (which left 70 patients in the analysis), death during hospital stay occurred less often in TH group (28.6% vs 57.1%, P=0.029), while the difference in CPC score was not significant. Cox proportional hazards model showed the predictors of death during hospital stay to be TH (hazard ratio [HR] 0.29, 95% confidence interval [CI] 0.13-0.68, P=0.004), initial Glasgow Coma Scale score of 3 (HR 7.55, 95% CI 1.44-39.63, P=0.017), and heart failure (HR 2.35, 95% CI 1.02-5.34, P=0.045). TH was not an independent predictor of CPC score. Mann-Whitney U test and linear regression model showed that TH was associated with higher gain in GCS. ----- Conclusion: TH was associated with better survival and certain variables suggesting improved neurological outcomes, suggesting that TH is a vital treatment option for comatose OHCA survivors.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCroatian Medical Journal
Brojčani podacivol. 61, br. 1, str. 40-48
p-ISSN0353-9504
e-ISSN1332-8166
DOIhttps://doi.org/10.3325/cmj.2020.61.40
URN:NBNurn:nbn:hr:105:017640
Datum objave publikacije2020-02-29
URL dokumentahttp://www.cmj.hr/2020/61/1/32118377.htm
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno-Bez prerada 4.0 međunarodna (CC BY-NC-ND 4.0)
Datum i vrijeme pohrane2020-10-29 11:47:16