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Epidemiological and clinical features of Croatian children and adolescents with a PCR-confirmed coronavirus disease 2019: differences between the first and second epidemic wave
Croatian Medical Journal, 61 (2020), 6; 491-500. https://doi.org/10.3325/cmj.2020.61.491
Krajcar, Nina; Stemberger Marić, Lorna; Šurina, Anja; Kurečić Filipović, Sanja; Trkulja, Vladimir; Roglić, Srđan; Tešović, Goran

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Institucijski repozitorij: Dr Med - digitalni repozitorij Medicinskog fakulteta Sveučilišta u Zagrebu

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Krajcar, N., Stemberger Marić, L., Šurina, A., Kurečić Filipović, S., Trkulja, V., Roglić, S. i Tešović, G. (2020). Epidemiological and clinical features of Croatian children and adolescents with a PCR-confirmed coronavirus disease 2019: differences between the first and second epidemic wave. Croatian Medical Journal, 61. (6), 491-500. doi: 10.3325/cmj.2020.61.491

Krajcar, Nina, et al. "Epidemiological and clinical features of Croatian children and adolescents with a PCR-confirmed coronavirus disease 2019: differences between the first and second epidemic wave." Croatian Medical Journal, vol. 61, br. 6, 2020, str. 491-500. https://doi.org/10.3325/cmj.2020.61.491

Krajcar, Nina, Lorna Stemberger Marić, Anja Šurina, Sanja Kurečić Filipović, Vladimir Trkulja, Srđan Roglić i Goran Tešović. "Epidemiological and clinical features of Croatian children and adolescents with a PCR-confirmed coronavirus disease 2019: differences between the first and second epidemic wave." Croatian Medical Journal 61, br. 6 (2020): 491-500. https://doi.org/10.3325/cmj.2020.61.491

Krajcar, N., et al. (2020) 'Epidemiological and clinical features of Croatian children and adolescents with a PCR-confirmed coronavirus disease 2019: differences between the first and second epidemic wave', Croatian Medical Journal, 61(6), str. 491-500. doi: 10.3325/cmj.2020.61.491

Krajcar N, Stemberger Marić L, Šurina A, Kurečić Filipović S, Trkulja V, Roglić S, i sur.. Epidemiological and clinical features of Croatian children and adolescents with a PCR-confirmed coronavirus disease 2019: differences between the first and second epidemic wave. Croatian Medical Journal [Internet]. 31.12.2020. [pristupljeno 24.12.2024.];61(6):491-500. doi: 10.3325/cmj.2020.61.491

N. Krajcar, et al., "Epidemiological and clinical features of Croatian children and adolescents with a PCR-confirmed coronavirus disease 2019: differences between the first and second epidemic wave", Croatian Medical Journal, vol. 61, br. 6, str. 491-500, Prosinac 2020. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:177121. [Citirano: 24.12.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:177121
Podaci o radu
Naslov (engleski)Epidemiological and clinical features of Croatian children and adolescents with a PCR-confirmed coronavirus disease 2019: differences between the first and second epidemic wave
AutorNina Krajcar
AutorLorna Stemberger Marić
AutorAnja Šurina
AutorSanja Kurečić Filipović
AutorVladimir Trkulja
AutorSrđan Roglić
AutorGoran Tešović
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INFEKTOLOGIJU)
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA TEMELJNU I KLINIČKU FARMAKOLOGIJU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Farmakologija
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Infektologija
Sažetak (engleski)
Aim: To describe epidemiological and clinical features of Croatian children and adolescents with a polymerase chain reaction (PCR)-confirmed coronavirus disease 2019. ----- Methods: Data on patients aged ≤19 years with a positive SARS-CoV-2 PCR test recorded in the period March 12-May 12 (first wave) and June 19-July 19, 2020 (second wave) were retrospectively analyzed. The periods were separated by several weeks with no incident cases. ----- Results: We analyzed data on 289 children and adolescents (6.5% of all cases; incidence rate [IR]=3.54, 95% confidence interval [CI] 3.14-3.97/million person-days), 124 in the first wave (IR=2.27) and 165 in the second wave (IR=6.37): IRR second/first=2.71 (2.13-3.44). During the first wave, the incidence was highest in infants (IR=3.48), while during the second wave it progressively increased to IR = 7.37 in 15-19-year olds. Family members were the key epidemiological contacts (72.6% cases), particularly during the first wave (95.8% vs 56.3%). Overall, 41.3% patients were asymptomatic, 25.3% in the first and 52.6% in the second wave. Age 15-19 years (vs younger) was associated with a higher (RR = 1.26, 1.02-1.54) and infection in the second wave with a lower probability (RR=0.66, 0.53-0.81) of being symptomatic. The most common symptoms were fever, cough, and rhinorrhea. In children aged ≥7 years, headache, anosmia/ageusia, and sore throat were also recorded. Only one child suffered a severe disease. All but 18 (7.8%) children were treated only symptomatically, and all fully recovered. ----- Conclusion: A large proportion of SARS-CoV-2 PCR-positive children/adolescents were asymptomatic. The associated disease was predominantly mild, comparably so in the first and second pandemic wave.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCroatian Medical Journal
Brojčani podacivol. 61, br. 6, str. 491-500
p-ISSN0353-9504
e-ISSN1332-8166
DOIhttps://doi.org/10.3325/cmj.2020.61.491
URN:NBNurn:nbn:hr:105:177121
Datum objave publikacije2020-12-31
URL dokumentahttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821366/
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno-Bez prerada 4.0 međunarodna (CC BY-NC-ND 4.0)
Datum i vrijeme pohrane2021-02-25 08:34:59