prikaz prve stranice dokumenta Liver and Nonliver-Related Outcomes at 2 Years Are Not Influenced by the Results of the FIB-4 Test and Liver Elastography in a Real-Life Cohort of Patients with Type 2 Diabetes
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Liver and Nonliver-Related Outcomes at 2 Years Are Not Influenced by the Results of the FIB-4 Test and Liver Elastography in a Real-Life Cohort of Patients with Type 2 Diabetes
Canadian Journal of Gastroenterology and Hepatology, 2021 (2021); 5582813. https://doi.org/10.1155/2021/5582813
Grgurević, Ivica; Salkić, Nermin; Mustapić, Sanda; Bokun, Tomislav; Podrug, Kristian; Marušić, Srećko; Rahelić, Dario; Matić, Tomas; Škurla, Viktoria; Mikolašević, Ivana

Institucijski repozitorij: Dr Med - digitalni repozitorij Medicinskog fakulteta Sveučilišta u Zagrebu

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Grgurević, I., Salkić, N., Mustapić, S., Bokun, T., Podrug, K., Marušić, S. ... Mikolašević, I. (2021). Liver and Nonliver-Related Outcomes at 2 Years Are Not Influenced by the Results of the FIB-4 Test and Liver Elastography in a Real-Life Cohort of Patients with Type 2 Diabetes. Canadian Journal of Gastroenterology and Hepatology, 2021.. doi: 10.1155/2021/5582813

Grgurević, Ivica, et al. "Liver and Nonliver-Related Outcomes at 2 Years Are Not Influenced by the Results of the FIB-4 Test and Liver Elastography in a Real-Life Cohort of Patients with Type 2 Diabetes." Canadian Journal of Gastroenterology and Hepatology, vol. 2021, 2021. https://doi.org/10.1155/2021/5582813

Grgurević, Ivica, Nermin Salkić, Sanda Mustapić, Tomislav Bokun, Kristian Podrug, Srećko Marušić, Dario Rahelić, Tomas Matić, Viktoria Škurla i Ivana Mikolašević. "Liver and Nonliver-Related Outcomes at 2 Years Are Not Influenced by the Results of the FIB-4 Test and Liver Elastography in a Real-Life Cohort of Patients with Type 2 Diabetes." Canadian Journal of Gastroenterology and Hepatology 2021 (2021). https://doi.org/10.1155/2021/5582813

Grgurević, I., et al. (2021) 'Liver and Nonliver-Related Outcomes at 2 Years Are Not Influenced by the Results of the FIB-4 Test and Liver Elastography in a Real-Life Cohort of Patients with Type 2 Diabetes', Canadian Journal of Gastroenterology and Hepatology, 2021. doi: 10.1155/2021/5582813

Grgurević I, Salkić N, Mustapić S, Bokun T, Podrug K, Marušić S, i sur.. Liver and Nonliver-Related Outcomes at 2 Years Are Not Influenced by the Results of the FIB-4 Test and Liver Elastography in a Real-Life Cohort of Patients with Type 2 Diabetes. Canadian Journal of Gastroenterology and Hepatology [Internet]. 08.03.2021. [pristupljeno 06.11.2024.];2021. doi: 10.1155/2021/5582813

I. Grgurević, et al., "Liver and Nonliver-Related Outcomes at 2 Years Are Not Influenced by the Results of the FIB-4 Test and Liver Elastography in a Real-Life Cohort of Patients with Type 2 Diabetes", Canadian Journal of Gastroenterology and Hepatology, vol. 2021, Ožujak 2021. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:158668. [Citirano: 06.11.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:158668
Podaci o radu
Naslov (engleski)Liver and Nonliver-Related Outcomes at 2 Years Are Not Influenced by the Results of the FIB-4 Test and Liver Elastography in a Real-Life Cohort of Patients with Type 2 Diabetes
AutorIvica Grgurević
AutorNermin Salkić
AutorSanda Mustapić
AutorTomislav Bokun
AutorKristian Podrug
AutorSrećko Marušić
AutorDario Rahelić
AutorTomas Matić
AutorViktoria Škurla
AutorIvana Mikolašević
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INTERNU MEDICINU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Aims. To investigate morbidity and mortality in a real-life cohort of patients with type 2 diabetes (T2D) in relation to prevalence and severity of nonalcoholic fatty liver disease (NAFLD). ----- Methods. Patients with T2D were referred for assessment of liver fibrosis by the FIB-4 test and liver stiffness measurement (LSM) by vibration-controlled transient elastography (VCTE). Liver steatosis was quantified by the controlled attenuation parameter (CAP). These patients were followed until death or censored date. ----- Results. Among 454 patients (52% males, mean age 62.5 years, BMI 30.9 kg/m2), 82.6% was overweight, 77.8% had fatty liver, and 9.9% and 3.1% had LSM and FIB-4 values suggestive of advanced fibrosis, respectively. During the follow-up period of median 2 years, 106 (23%) patients experienced adverse event (11% cardiovascular) and 17 (3.7%) died, whereas no liver-related morbidity or mortality was observed. Independent predictors of adverse outcomes were age and higher platelet count, while FIB-4, LSM, and CAP were not. ----- Conclusion. In a cohort of T2D patients, no liver-related morbidity or mortality occurred during 2 years. Our patients probably have low real prevalence of advanced fibrosis which is likely overestimated by LSM ≥ 9.6 kPa. Liver fibrosis may be safely reassessed in the 2 years interval in noncirrhotic patients with T2D.
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCanadian Journal of Gastroenterology and Hepatology
Brojčani podacivol. 2021, 5582813
p-ISSN2291-2789
e-ISSN2291-2797
DOIhttps://doi.org/10.1155/2021/5582813
URN:NBNurn:nbn:hr:105:158668
Datum objave publikacije2021-03-08
URL dokumentahttps://www.hindawi.com/journals/cjgh/2021/5582813/
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2021-05-20 08:38:04