prikaz prve stranice dokumenta Immune-mediated diseases after coronavirus disease 2019 vaccination: rare but important complication
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Immune-mediated diseases after coronavirus disease 2019 vaccination: rare but important complication
Croatian Medical Journal, 63 (2022), 4; 389-393. https://doi.org/10.3325/cmj.2022.63.389
Zagorec, Nikola; Horvatić, Ivica; Šenjug, Petar; Horaček, Matija; Galešić Ljubanović, Danica; Galešić, Krešimir

Institucijski repozitorij: Dr Med - digitalni repozitorij Medicinskog fakulteta Sveučilišta u Zagrebu

Citirajte ovaj rad

Zagorec, N., Horvatić, I., Šenjug, P., Horaček, M., Galešić Ljubanović, D. i Galešić, K. (2022). Immune-mediated diseases after coronavirus disease 2019 vaccination: rare but important complication. Croatian Medical Journal, 63. (4), 389-393. doi: 10.3325/cmj.2022.63.389

Zagorec, Nikola, et al. "Immune-mediated diseases after coronavirus disease 2019 vaccination: rare but important complication." Croatian Medical Journal, vol. 63, br. 4, 2022, str. 389-393. https://doi.org/10.3325/cmj.2022.63.389

Zagorec, Nikola, Ivica Horvatić, Petar Šenjug, Matija Horaček, Danica Galešić Ljubanović i Krešimir Galešić. "Immune-mediated diseases after coronavirus disease 2019 vaccination: rare but important complication." Croatian Medical Journal 63, br. 4 (2022): 389-393. https://doi.org/10.3325/cmj.2022.63.389

Zagorec, N., et al. (2022) 'Immune-mediated diseases after coronavirus disease 2019 vaccination: rare but important complication', Croatian Medical Journal, 63(4), str. 389-393. doi: 10.3325/cmj.2022.63.389

Zagorec N, Horvatić I, Šenjug P, Horaček M, Galešić Ljubanović D, Galešić K. Immune-mediated diseases after coronavirus disease 2019 vaccination: rare but important complication. Croatian Medical Journal [Internet]. 31.08.2022. [pristupljeno 29.12.2024.];63(4):389-393. doi: 10.3325/cmj.2022.63.389

N. Zagorec, I. Horvatić, P. Šenjug, M. Horaček, D. Galešić Ljubanović i K. Galešić, "Immune-mediated diseases after coronavirus disease 2019 vaccination: rare but important complication", Croatian Medical Journal, vol. 63, br. 4, str. 389-393, Kolovoz 2022. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:149922. [Citirano: 29.12.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:149922
Podaci o radu
Naslov (engleski)Immune-mediated diseases after coronavirus disease 2019 vaccination: rare but important complication
AutorNikola Zagorec
AutorIvica Horvatić
AutorPetar Šenjug
AutorMatija Horaček
AutorDanica Galešić Ljubanović
AutorKrešimir Galešić
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INTERNU MEDICINU)
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA PATOLOGIJU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Patologija
Sažetak (engleski)
Since the beginning of mass vaccination against coronavirus disease 2019 (COVID-19), vaccine-linked immune-mediated diseases have been increasingly reported. The development of these diseases after COVID-19 vaccination may be attributed to the mechanisms of molecular mimicry and cross-reactivity between the viral spike protein and self-antigens. The most frequent vaccine-linked glomerular disease is immunoglobulin A nephropathy (IgAN). Cutaneous vasculitis has also been reported after COVID-19 vaccination. In both diseases, deposition of immune complexes activates the inflammatory response with end-organ damage. We report on a case of de novo IgAN in a young man and a case of severe cutaneous vasculitis in a 68-year-old woman, both after the second dose of Pfizer-BioNTech COVID-19 vaccine. Neither of the patients had a history of autoimmunity or adverse reactions to vaccines. The temporal association between vaccination and disease development in the absence of other possible intercurrent inciting events suggests a causal mechanism, although coincidental co-occurrence cannot be excluded. In both cases, immunosuppressive treatment was warranted to stop disease progression and to partially or completely resolve the disease. A timely reaction is needed if new-onset signs of an immune-mediated disease appear after vaccination.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Prikaz slučaja
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCroatian Medical Journal
Brojčani podacivol. 63, br. 4, str. 389-393
p-ISSN0353-9504
e-ISSN1332-8166
DOIhttps://doi.org/10.3325/cmj.2022.63.389
URN:NBNurn:nbn:hr:105:149922
Datum objave publikacije2022-08-31
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno-Bez prerada 4.0 međunarodna (CC BY-NC-ND 4.0)
Datum i vrijeme pohrane2022-09-26 08:23:07