prikaz prve stranice dokumenta Point Shear Wave Elastography by ElastPQ for Fibrosis Screening in Patients with NAFLD: A Prospective, Multicenter Comparison to Vibration-Controlled Elastography
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Point Shear Wave Elastography by ElastPQ for Fibrosis Screening in Patients with NAFLD: A Prospective, Multicenter Comparison to Vibration-Controlled Elastography
Ultraschall in der Medizin - European Journal of Ultrasound, 44 (2022), 02; 169-178. https://doi.org/10.1055/a-1724-7289
Bauer, David JM; Matić, Vladimir; Mare, Ruxandra; Maiocchi, Laura; Chromy, David; Müllner-Bucsics, Theresa; Mandorfer, Mattias; Mustapić, Sandra; Sporea, Ioan; Ferraioli, Giovanna; Grgurević, Ivica; Reiberger, Thomas

Institucijski repozitorij: Dr Med - digitalni repozitorij Medicinskog fakulteta Sveučilišta u Zagrebu

Citirajte ovaj rad

Bauer, D. J., Matić, V., Mare, R., Maiocchi, L., Chromy, D., Müllner Bucsics, T. ... Reiberger, T. (2022). Point Shear Wave Elastography by ElastPQ for Fibrosis Screening in Patients with NAFLD: A Prospective, Multicenter Comparison to Vibration-Controlled Elastography. Ultraschall in der Medizin - European Journal of Ultrasound, 44. (02), 169-178. doi: 10.1055/a-1724-7289

Bauer, David JM, et al. "Point Shear Wave Elastography by ElastPQ for Fibrosis Screening in Patients with NAFLD: A Prospective, Multicenter Comparison to Vibration-Controlled Elastography." Ultraschall in der Medizin - European Journal of Ultrasound, vol. 44, br. 02, 2022, str. 169-178. https://doi.org/10.1055/a-1724-7289

Bauer, David JM, Vladimir Matić, Ruxandra Mare, Laura Maiocchi, David Chromy, Theresa Müllner Bucsics, Mattias Mandorfer, et al. "Point Shear Wave Elastography by ElastPQ for Fibrosis Screening in Patients with NAFLD: A Prospective, Multicenter Comparison to Vibration-Controlled Elastography." Ultraschall in der Medizin - European Journal of Ultrasound 44, br. 02 (2022): 169-178. https://doi.org/10.1055/a-1724-7289

Bauer, D. J., et al. (2022) 'Point Shear Wave Elastography by ElastPQ for Fibrosis Screening in Patients with NAFLD: A Prospective, Multicenter Comparison to Vibration-Controlled Elastography', Ultraschall in der Medizin - European Journal of Ultrasound, 44(02), str. 169-178. doi: 10.1055/a-1724-7289

Bauer DJ, Matić V, Mare R, Maiocchi L, Chromy D, Müllner Bucsics T, i sur.. Point Shear Wave Elastography by ElastPQ for Fibrosis Screening in Patients with NAFLD: A Prospective, Multicenter Comparison to Vibration-Controlled Elastography. Ultraschall in der Medizin - European Journal of Ultrasound [Internet]. 28.02.2022. [pristupljeno 24.11.2024.];44(02):169-178. doi: 10.1055/a-1724-7289

D. J. Bauer, et al., "Point Shear Wave Elastography by ElastPQ for Fibrosis Screening in Patients with NAFLD: A Prospective, Multicenter Comparison to Vibration-Controlled Elastography", Ultraschall in der Medizin - European Journal of Ultrasound, vol. 44, br. 02, str. 169-178, Veljača 2022. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:708121. [Citirano: 24.11.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:708121
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Naslov (engleski)Point Shear Wave Elastography by ElastPQ for Fibrosis Screening in Patients with NAFLD: A Prospective, Multicenter Comparison to Vibration-Controlled Elastography
AutorDavid JM Bauer
AutorVladimir Matić
MBZ: 142564
AutorRuxandra Mare
AutorLaura Maiocchi
AutorDavid Chromy
AutorTheresa Müllner-Bucsics
AutorMattias Mandorfer
AutorSandra Mustapić
AutorIoan Sporea
AutorGiovanna Ferraioli
AutorIvica Grgurević
AutorThomas Reiberger
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INTERNU MEDICINU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Background: Since nonalcoholic fatty liver disease (NAFLD) has become the leading cause of liver disease in the Western world, clinicians need reliable noninvasive tools for the identification of NAFLD-associated fibrosis. Limited evidence on the performance of the novel shear wave elastography technique Elast-PQ (EPQ) in NAFLD is available. Method: In this prospective, European multinational study we assessed the diagnostic accuracy of EPQ using vibration-controlled transient elastography (VCTE) as a reference standard. Results: Among 353 NAFLD patients, 332 (94.1%) fulfilled reliability criteria of VCTE and EPQ (defined by IQR/median ≤0.3; 41.3% female, mean age: 59 [IQR: 16.5], mean BMI: 29.0 (7.1)). 4/353 (1.1%) and 17/353 (4.8%) had unreliable VCTE and EPQ measurements, respectively. VCTE-based NAFLD fibrosis stages were F0/F1: 222(66.9%), F2: 41 (12.3%), F3: 30 (9.1%), F4: 39 (11.7%). We found a strong correlation (Pearson R=0.87; p<0.0001) and concordance (Lin's concordance correlation coefficient =0.792) of EPQ with VCTE. EPQ was able to identify NAFLD-fibrosis risk with the following EPQ cutoffs: ≥6.5 kPa for significant fibrosis (≥F2) (≥1.47 m/s; sensitivity: 78%; specificity: 95%; AUROC: 0.94), ≥6.9 kPa for advanced fibrosis (≥F3) (≥1.52 m/s; sens.: 88%, spec.: 89%; AUROC: 0.949), and ≥10.4 kPa for cirrhosis (F4) (≥1.86 m/s; sens.: 87%; spec.: 94%; AUROC: 0.949). Conclusion: The point shear wave elastography technique EPQ shows excellent correlation to and concordance with VCTE. EPQ can reliably exclude NAFLD fibrosis <6.0 kPa (<1.41 m/s) and indicate a high risk of advanced fibrosis ≥10.4 kPa (≥1.86 m/s).
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaUltraschall in der Medizin - European Journal of Ultrasound
Brojčani podacivol. 44, br. 02, str. 169-178
p-ISSN0172-4614
e-ISSN1438-8782
DOIhttps://doi.org/10.1055/a-1724-7289
URN:NBNurn:nbn:hr:105:708121
Datum objave publikacije2022-02-28
URL dokumentahttp://www.thieme-connect.de/DOI/DOI?10.1055/a-1724-7289
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno-Bez prerada 4.0 međunarodna (CC BY-NC-ND 4.0)
Datum i vrijeme pohrane2023-08-31 08:22:31