prikaz prve stranice dokumenta Investigating the role of obstructive pulmonary diseases and eosinophil count at admission on all-cause mortality in SARS-CoV-2 patients
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Investigating the role of obstructive pulmonary diseases and eosinophil count at admission on all-cause mortality in SARS-CoV-2 patients
Wiener klinische Wochenschrift, 135 (2023), 9-10; 235-243. https://doi.org/10.1007/s00508-023-02180-w
Salai, Grgur; Vražić, Hrvoje; Kovačević, Ivona; Malnar Janeš, Linda; Marasović, Ivan; Ranilović, Darjan; Vukoja, Damir; Zelenika Margeta, Marina; Huljev–ŠipoŠ, Ivana; Lalić, Kristina; Špoljarić, Marko; Tekavec-Trkanjec, Jasna; Vergles, Mirna; Lucijanić, Marko; Lukšić, Ivica; Ljubičić, Đivo Više autora...

Institucijski repozitorij: Dr Med - digitalni repozitorij Medicinskog fakulteta Sveučilišta u Zagrebu

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Salai, G., Vražić, H., Kovačević, I., Malnar Janeš, L., Marasović, I., Ranilović, D. ... Ljubičić, Đ. (2023). Investigating the role of obstructive pulmonary diseases and eosinophil count at admission on all-cause mortality in SARS-CoV-2 patients. Wiener klinische Wochenschrift, 135. (9-10), 235-243. doi: 10.1007/s00508-023-02180-w

Salai, Grgur, et al. "Investigating the role of obstructive pulmonary diseases and eosinophil count at admission on all-cause mortality in SARS-CoV-2 patients." Wiener klinische Wochenschrift, vol. 135, br. 9-10, 2023, str. 235-243. https://doi.org/10.1007/s00508-023-02180-w

Salai, Grgur, Hrvoje Vražić, Ivona Kovačević, Linda Malnar Janeš, Ivan Marasović, Darjan Ranilović, Damir Vukoja, et al. "Investigating the role of obstructive pulmonary diseases and eosinophil count at admission on all-cause mortality in SARS-CoV-2 patients." Wiener klinische Wochenschrift 135, br. 9-10 (2023): 235-243. https://doi.org/10.1007/s00508-023-02180-w

Salai, G., et al. (2023) 'Investigating the role of obstructive pulmonary diseases and eosinophil count at admission on all-cause mortality in SARS-CoV-2 patients', Wiener klinische Wochenschrift, 135(9-10), str. 235-243. doi: 10.1007/s00508-023-02180-w

Salai G, Vražić H, Kovačević I, Malnar Janeš L, Marasović I, Ranilović D, i sur.. Investigating the role of obstructive pulmonary diseases and eosinophil count at admission on all-cause mortality in SARS-CoV-2 patients. Wiener klinische Wochenschrift [Internet]. 05.2023. [pristupljeno 24.12.2024.];135(9-10):235-243. doi: 10.1007/s00508-023-02180-w

G. Salai, et al., "Investigating the role of obstructive pulmonary diseases and eosinophil count at admission on all-cause mortality in SARS-CoV-2 patients", Wiener klinische Wochenschrift, vol. 135, br. 9-10, str. 235-243, Svibanj 2023. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:101032. [Citirano: 24.12.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:101032
Podaci o radu
Naslov (engleski)Investigating the role of obstructive pulmonary diseases and eosinophil count at admission on all-cause mortality in SARS-CoV-2 patients
AutorGrgur Salai
AutorHrvoje Vražić
AutorIvona Kovačević
AutorLinda Malnar Janeš
AutorIvan Marasović
AutorDarjan Ranilović
AutorDamir Vukoja
AutorMarina Zelenika Margeta
AutorIvana Huljev–ŠipoŠ
AutorKristina Lalić
AutorMarko Špoljarić
AutorJasna Tekavec-Trkanjec
AutorMirna Vergles
AutorMarko Lucijanić
AutorIvica Lukšić
AutorĐivo Ljubičić
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INTERNU MEDICINU)
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA MAKSILOFACIJALNU KIRURGIJU SA STOMATOLOGIJOM)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Kirurgija
Sažetak (engleski)
Introduction: The impact of asthma and chronic obstructive pulmonary disease (COPD) in the setting of severe acute respiratory syndrome coronavirus 2 (SARS-CoV‑2) infection is not clearly defined. Blood eosinophil count is a standard diagnostic test which, according to the previously published literature, might have a potential prognostic role on mortality in patients with SARS-CoV‑2 infection. Aim: To investigate the potential prognostic value of peripheral blood eosinophil count on all-cause mortality of patients hospitalized with SARS-CoV‑2 infection, as well as to assess the impact of asthma or COPD premorbidity on all-cause mortality. Material and methods: We conducted a retrospective registry-based cohort study. Survival analysis was performed by employing the Cox proportional hazards regression model at 30 days of follow-up. Prognostic value of eosinophil count on all-cause mortality was assessed using receiver-operating characteristic (ROC) curve analysis. Results: A total of 5653 participants were included in the study. Our model did not reveal that pre-existing asthma or COPD is a statistically significant covariate for all-cause mortality but, indicated that higher eosinophil count at admission might have a protective effect (hazard ratio, HR 0.13 (95% confidence interval, CI 0.06-0.27), p = 0.0001). ROC curve analysis indicates cut-off value of 20 cells/mm3 (81% specificity; 30.9% sensitivity). Conclusion: Our results indicate that eosinophil count at hospital admission might have a potential prognostic role for all-cause mortality at 30 days of follow-up; however this was not demonstrated for pre-existing obstructive lung diseases.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaWiener klinische Wochenschrift
Brojčani podacivol. 135, br. 9-10, str. 235-243
p-ISSN0043-5325
e-ISSN1613-7671
DOIhttps://doi.org/10.1007/s00508-023-02180-w
URN:NBNurn:nbn:hr:105:101032
Datum objave publikacije2023-05
URL dokumentahttps://link.springer.com/10.1007/s00508-023-02180-w
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2023-11-21 09:17:10