prikaz prve stranice dokumenta Increased carotid intima-media thickness is associated with higher odds of unfavorable outcomes in adults without advanced vascular diseases presenting with non-severe COVID-19 pneumonia: a nested case-control study
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Increased carotid intima-media thickness is associated with higher odds of unfavorable outcomes in adults without advanced vascular diseases presenting with non-severe COVID-19 pneumonia: a nested case-control study
Croatian Medical Journal, 64 (2023), 5; 344-353. https://doi.org/10.3325/cmj.2023.64.344
Crnjaković, Miljenko; Deveđija, Sabina; Vukorepa, Gorana; Rutović, Stela; Sporiš, Davor; Trkulja, Vladimir

Institucijski repozitorij: Dr Med - digitalni repozitorij Medicinskog fakulteta Sveučilišta u Zagrebu

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Crnjaković, M., Deveđija, S., Vukorepa, G., Rutović, S., Sporiš, D. i Trkulja, V. (2023). Increased carotid intima-media thickness is associated with higher odds of unfavorable outcomes in adults without advanced vascular diseases presenting with non-severe COVID-19 pneumonia: a nested case-control study. Croatian Medical Journal, 64. (5), 344-353. doi: 10.3325/cmj.2023.64.344

Crnjaković, Miljenko, et al. "Increased carotid intima-media thickness is associated with higher odds of unfavorable outcomes in adults without advanced vascular diseases presenting with non-severe COVID-19 pneumonia: a nested case-control study." Croatian Medical Journal, vol. 64, br. 5, 2023, str. 344-353. https://doi.org/10.3325/cmj.2023.64.344

Crnjaković, Miljenko, Sabina Deveđija, Gorana Vukorepa, Stela Rutović, Davor Sporiš i Vladimir Trkulja. "Increased carotid intima-media thickness is associated with higher odds of unfavorable outcomes in adults without advanced vascular diseases presenting with non-severe COVID-19 pneumonia: a nested case-control study." Croatian Medical Journal 64, br. 5 (2023): 344-353. https://doi.org/10.3325/cmj.2023.64.344

Crnjaković, M., et al. (2023) 'Increased carotid intima-media thickness is associated with higher odds of unfavorable outcomes in adults without advanced vascular diseases presenting with non-severe COVID-19 pneumonia: a nested case-control study', Croatian Medical Journal, 64(5), str. 344-353. doi: 10.3325/cmj.2023.64.344

Crnjaković M, Deveđija S, Vukorepa G, Rutović S, Sporiš D, Trkulja V. Increased carotid intima-media thickness is associated with higher odds of unfavorable outcomes in adults without advanced vascular diseases presenting with non-severe COVID-19 pneumonia: a nested case-control study. Croatian Medical Journal [Internet]. 31.10.2023. [pristupljeno 15.05.2024.];64(5):344-353. doi: 10.3325/cmj.2023.64.344

M. Crnjaković, S. Deveđija, G. Vukorepa, S. Rutović, D. Sporiš i V. Trkulja, "Increased carotid intima-media thickness is associated with higher odds of unfavorable outcomes in adults without advanced vascular diseases presenting with non-severe COVID-19 pneumonia: a nested case-control study", Croatian Medical Journal, vol. 64, br. 5, str. 344-353, Listopad 2023. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:860728. [Citirano: 15.05.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:860728
Podaci o radu
Naslov (engleski)Increased carotid intima-media thickness is associated with higher odds of unfavorable outcomes in adults without advanced vascular diseases presenting with non-severe COVID-19 pneumonia: a nested case-control study
AutorMiljenko Crnjaković
AutorSabina Deveđija
AutorGorana Vukorepa
AutorStela Rutović
AutorDavor Sporiš
AutorVladimir Trkulja
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA TEMELJNU I KLINIČKU FARMAKOLOGIJU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Farmakologija
Sažetak (engleski)
Aim: To evaluate the association between carotid intima-media thickness (CIMT) at hospital admission and unfavorable outcomes in adults without advanced vascular diseases presenting with non-severe COVID-19 pneumonia to assess the feasibility of evaluating CIMT as a risk stratification aid in this setting. Methods: This proof-of-concept nested case-control study enrolled consecutive non-vaccinated adults free of advanced vascular diseases presenting with verified non-severe COVID-19 pneumonia between December 2020 and June 2021. CIMT was measured at admission, and patients were managed in line with the national Ministry of Health guidelines. Those who died or required mechanical ventilation (MV) during the index hospital stay were considered cases and were matched (entropy balancing, exact matching) on a set of covariates to survivors not requiring MV (controls). Frequentist and Bayesian logistic models were fitted to the case status. Results: The study enrolled 207 patients: 27 (13%) cases and 180 controls. All were retained in the analysis after entropy balancing, while 27 cases were exactly matched to 99 controls. Higher CIMT at the proximal internal carotid artery (both left and right) was consistently associated with higher odds of being a case: all odds ratio point-estimates were ≥1.50 with lower limits of the 99% confidence intervals/credibility intervals ≥1.00 with two-sided probabilities of OR>1.00 greater than 99.5%. The susceptibility of the estimates to unmeasured confounding was low. Conclusion: This study supports the feasibility of CIMT as a risk stratification aid in adults free of advanced vascular disease presenting with non-severe COVID-19 pneumonia.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCroatian Medical Journal
Brojčani podacivol. 64, br. 5, str. 344-353
p-ISSN0353-9504
e-ISSN1332-8166
DOIhttps://doi.org/10.3325/cmj.2023.64.344
URN:NBNurn:nbn:hr:105:860728
Datum objave publikacije2023-10-31
URL dokumentahttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668038/
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno-Bez prerada 4.0 međunarodna (CC BY-NC-ND 4.0)
Datum i vrijeme pohrane2024-01-09 13:11:31