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Diagnostic and Management Strategies of IgA Vasculitis Nephritis/Henoch-Schönlein Purpura Nephritis in Pediatric Patients: Current Perspectives
Pediatric Health, Medicine and Therapeutics, 14 (2023); 89-98. https://doi.org/10.2147/PHMT.S379862
Šestan, Mario; Jelušić, Marija

Institucijski repozitorij: Dr Med - digitalni repozitorij Medicinskog fakulteta Sveučilišta u Zagrebu

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Šestan, M. i Jelušić, M. (2023). Diagnostic and Management Strategies of IgA Vasculitis Nephritis/Henoch-Schönlein Purpura Nephritis in Pediatric Patients: Current Perspectives. Pediatric Health, Medicine and Therapeutics, 14., 89-98. doi: 10.2147/PHMT.S379862

Šestan, Mario i Marija Jelušić. "Diagnostic and Management Strategies of IgA Vasculitis Nephritis/Henoch-Schönlein Purpura Nephritis in Pediatric Patients: Current Perspectives." Pediatric Health, Medicine and Therapeutics, vol. 14, 2023, str. 89-98. https://doi.org/10.2147/PHMT.S379862

Šestan, Mario i Marija Jelušić. "Diagnostic and Management Strategies of IgA Vasculitis Nephritis/Henoch-Schönlein Purpura Nephritis in Pediatric Patients: Current Perspectives." Pediatric Health, Medicine and Therapeutics 14 (2023): 89-98. https://doi.org/10.2147/PHMT.S379862

Šestan, M. i Jelušić, M. (2023) 'Diagnostic and Management Strategies of IgA Vasculitis Nephritis/Henoch-Schönlein Purpura Nephritis in Pediatric Patients: Current Perspectives', Pediatric Health, Medicine and Therapeutics, 14, str. 89-98. doi: 10.2147/PHMT.S379862

Šestan M, Jelušić M. Diagnostic and Management Strategies of IgA Vasculitis Nephritis/Henoch-Schönlein Purpura Nephritis in Pediatric Patients: Current Perspectives. Pediatric Health, Medicine and Therapeutics [Internet]. 07.03.2023. [pristupljeno 12.01.2025.];14:89-98. doi: 10.2147/PHMT.S379862

M. Šestan i M. Jelušić, "Diagnostic and Management Strategies of IgA Vasculitis Nephritis/Henoch-Schönlein Purpura Nephritis in Pediatric Patients: Current Perspectives", Pediatric Health, Medicine and Therapeutics, vol. 14, str. 89-98, Ožujak 2023. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:542113. [Citirano: 12.01.2025.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:542113
Podaci o radu
Naslov (engleski)Diagnostic and Management Strategies of IgA Vasculitis Nephritis/Henoch-Schönlein Purpura Nephritis in Pediatric Patients: Current Perspectives
AutorMario Šestan
AutorMarija Jelušić
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA PEDIJATRIJU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Pedijatrija
Sažetak (engleski)
IgA vasculitis (IgAV) or Henoch-Schönlein purpura (HSP) is the most common vasculitis in children, and nephritis (IgAVN or HSPN) is the most important and only chronic manifestation of the disease. Despite this, there are no diagnostic criteria and we rely on the European League Against Rheumatism/Paediatric Rheumatology International Trials Organization/Paediatric Rheumatology European Society-endorsed Ankara 2008 classification criteria in our daily practice. Basic investigations that should be done in every patient with IgAVN include blood pressure measurement, estimated glomerular filtration rate and urinalysis. Kidney biopsy is still the gold standard for the diagnosis of IgAVN since noninvasive confirmation of nephritis is still pending. According to the Single Hub and Access point for pediatric Rheumatology in Europe (SHARE) recommendations, the first-line treatment for with mild forms of IgAVN is oral glucocorticoids, for patients with moderate IgAVN parenterally administrated glucocorticoids in pulsed doses, while initial treatment for patients with the most severe forms of IgAVN include pulsed doses of glucocorticoids in combination with intravenous cyclophosphamide pulses. New therapeutic options are currently being tested, aiming to reduce the production of galactose-deficient IgA1 and autoantibodies or suppress the alternative or lectin complement pathway and blocking mesangial cell activation.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Pregledni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaPediatric Health, Medicine and Therapeutics
Brojčani podacivol. 14, str. 89-98
e-ISSN1179-9927
DOIhttps://doi.org/10.2147/PHMT.S379862
URN:NBNurn:nbn:hr:105:542113
Datum objave publikacije2023-03-07
URL dokumentahttps://www.dovepress.com/diagnostic-and-management-strategies-of-iga-vasculitis-nephritishenoch-peer-reviewed-fulltext-article-PHMT
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno 3.0 (CC BY-NC 3.0)
Datum i vrijeme pohrane2024-01-11 10:12:38