prikaz prve stranice dokumenta Relationship of bone mineral density with disease activity and functional ability in patients with ankylosing spondylitis: a cross-sectional study
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Relationship of bone mineral density with disease activity and functional ability in patients with ankylosing spondylitis: a cross-sectional study
Rheumatology International, 32 (2012), 9; 2801-2808. https://doi.org/10.1007/s00296-011-2066-9
Grazio, Simeon; Kusić, Zvonko; Cvijetić, Selma; Grubišić, Frane; Balenović, Antonija; Nemčić, Tomislav; Matijević-Mikelić, Valentina; Punda, Marija; Sieper, Joachim

Institucijski repozitorij: Dr Med - digitalni repozitorij Medicinskog fakulteta Sveučilišta u Zagrebu

Citirajte ovaj rad

Grazio, S., Kusić, Z., Cvijetić, S., Grubišić, F., Balenović, A., Nemčić, T. ... Sieper, J. (2012). Relationship of bone mineral density with disease activity and functional ability in patients with ankylosing spondylitis: a cross-sectional study. Rheumatology International, 32. (9), 2801-2808. doi: 10.1007/s00296-011-2066-9

Grazio, Simeon, et al. "Relationship of bone mineral density with disease activity and functional ability in patients with ankylosing spondylitis: a cross-sectional study." Rheumatology International, vol. 32, br. 9, 2012, str. 2801-2808. https://doi.org/10.1007/s00296-011-2066-9

Grazio, Simeon, Zvonko Kusić, Selma Cvijetić, Frane Grubišić, Antonija Balenović, Tomislav Nemčić, Valentina Matijević Mikelić, Marija Punda i Joachim Sieper. "Relationship of bone mineral density with disease activity and functional ability in patients with ankylosing spondylitis: a cross-sectional study." Rheumatology International 32, br. 9 (2012): 2801-2808. https://doi.org/10.1007/s00296-011-2066-9

Grazio, S., et al. (2012) 'Relationship of bone mineral density with disease activity and functional ability in patients with ankylosing spondylitis: a cross-sectional study', Rheumatology International, 32(9), str. 2801-2808. doi: 10.1007/s00296-011-2066-9

Grazio S, Kusić Z, Cvijetić S, Grubišić F, Balenović A, Nemčić T, i sur.. Relationship of bone mineral density with disease activity and functional ability in patients with ankylosing spondylitis: a cross-sectional study. Rheumatology International [Internet]. 09.2012. [pristupljeno 14.01.2025.];32(9):2801-2808. doi: 10.1007/s00296-011-2066-9

S. Grazio, et al., "Relationship of bone mineral density with disease activity and functional ability in patients with ankylosing spondylitis: a cross-sectional study", Rheumatology International, vol. 32, br. 9, str. 2801-2808, Rujan 2012. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:714535. [Citirano: 14.01.2025.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:714535
Podaci o radu
Naslov (engleski)Relationship of bone mineral density with disease activity and functional ability in patients with ankylosing spondylitis: a cross-sectional study
AutorSimeon Grazio
AutorZvonko Kusić
AutorSelma Cvijetić
AutorFrane Grubišić
AutorAntonija Balenović
AutorTomislav Nemčić
AutorValentina Matijević-Mikelić
AutorMarija Punda
AutorJoachim Sieper
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
In ankylosing spondylitis, inflammatory activity probably plays a key role in the pathophysiology of bone loss. The aim of the study was to investigate the relationship of bone mineral density (BMD) at the lumbar spine and hip region with some measures of disease activity and functional ability in patients with ankylosing spondylitis. In 80 patients with established ankylosing spondylitis, disease activity and functional ability were determined by C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) and Bath Ankylosing Spondylitis Functional Index (BASFI). Spinal pain and patient global health were assessed using horizontal visual analog scale. BMD was measured by dual-energy X-ray absorptiometry. There was a significant negative correlation of bone density T scores with acute-phase reactants (i.e., patients with lower T scores had higher level of CRP and ESR). That relationship was reflected more reliably at proximal femur sites than at the lumbar spine. There were also significant differences in ESR, BASDAI, BASFI, spinal pain and global health between three groups of patients according to WHO classification of osteoporosis (normal, osteopenic and osteoporotic). Significantly, more patients with osteopenia at the lumbar spine had lower BASDAI index than those with normal BMD (P = 0.030). Our results indicate an association of low BMD with high disease activity in patients with AS. Femoral BMD seems to be more associated with disease activity and functional ability than lumbar spine BMD.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeZavršna verzija rukopisa prihvaćena za objavljivanje (postprint)
Naslov časopisaRheumatology International
Brojčani podacivol. 32, br. 9, str. 2801-2808
p-ISSN0172-8172
DOIhttps://doi.org/10.1007/s00296-011-2066-9
URN:NBNurn:nbn:hr:105:714535
Datum objave publikacije2012-09
URL dokumentahttps://doi.org/10.1007/s00296-011-2066-9
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2024-03-27 19:31:24