prikaz prve stranice dokumenta Intracranial thrombus morphology and composition undergoes time-dependent changes in acute ischemic stroke: a CT densitometry study
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Intracranial thrombus morphology and composition undergoes time-dependent changes in acute ischemic stroke: a CT densitometry study
International Journal of Molecular Sciences, 17 (2016), 11; E1959. https://doi.org/10.3390/ijms17111959
Pikija, Slaven; Magdič, Jožef; Trkulja, Vladimir; Unterkreuter, Peter; Mutzenbach, Johannes; Novak, Helmut; Weymayr, Friedrich; Hauer, Larissa; Sellner, Johann

Institucijski repozitorij: Dr Med - digitalni repozitorij Medicinskog fakulteta Sveučilišta u Zagrebu

Citirajte ovaj rad

Pikija, S., Magdič, J., Trkulja, V., Unterkreuter, P., Mutzenbach, J., Novak, H. ... Sellner, J. (2016). Intracranial thrombus morphology and composition undergoes time-dependent changes in acute ischemic stroke: a CT densitometry study. International Journal of Molecular Sciences, 17. (11), E1959. doi: 10.3390/ijms17111959

Pikija, Slaven, et al. "Intracranial thrombus morphology and composition undergoes time-dependent changes in acute ischemic stroke: a CT densitometry study." International Journal of Molecular Sciences, vol. 17, br. 11, 2016, str. E1959. https://doi.org/10.3390/ijms17111959

Pikija, Slaven, Jožef Magdič, Vladimir Trkulja, Peter Unterkreuter, Johannes Mutzenbach, Helmut Novak, Friedrich Weymayr, Larissa Hauer i Johann Sellner. "Intracranial thrombus morphology and composition undergoes time-dependent changes in acute ischemic stroke: a CT densitometry study." International Journal of Molecular Sciences 17, br. 11 (2016): E1959. https://doi.org/10.3390/ijms17111959

Pikija, S., et al. (2016) 'Intracranial thrombus morphology and composition undergoes time-dependent changes in acute ischemic stroke: a CT densitometry study', International Journal of Molecular Sciences, 17(11), str. E1959. doi: 10.3390/ijms17111959

Pikija S, Magdič J, Trkulja V, Unterkreuter P, Mutzenbach J, Novak H, i sur.. Intracranial thrombus morphology and composition undergoes time-dependent changes in acute ischemic stroke: a CT densitometry study. International Journal of Molecular Sciences [Internet]. 23.11.2016. [pristupljeno 15.05.2024.];17(11):E1959. doi: 10.3390/ijms17111959

S. Pikija, et al., "Intracranial thrombus morphology and composition undergoes time-dependent changes in acute ischemic stroke: a CT densitometry study", International Journal of Molecular Sciences, vol. 17, br. 11, str. E1959, Studeni 2016. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:397035. [Citirano: 15.05.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:397035
Podaci o radu
Naslov (engleski)Intracranial thrombus morphology and composition undergoes time-dependent changes in acute ischemic stroke: a CT densitometry study
AutorSlaven Pikija
AutorJožef Magdič
AutorVladimir Trkulja
AutorPeter Unterkreuter
AutorJohannes Mutzenbach
AutorHelmut Novak
AutorFriedrich Weymayr
AutorLarissa Hauer
AutorJohann Sellner
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
The aim of our study was to assess whether cerebral artery clots undergo time-dependent morphological and compositional changes in acute ischemic stroke. We performed a retrospective chart review of patients admitted within 5 h from symptom onset to three European stroke centers and evaluated non-contrast-enhanced CT (NECT) for hyperdense artery signs (HAS) in 2565 scans. The occlusion site, density of HAS expressed in Hounsfield units (HU), area of HAS, and relative density (rHU) (HU clot/HU non-affected artery) were studied and related to time from symptom onset, clinical severity, stroke etiology, and laboratory parameters. A HAS was present in the middle cerebral artery (MCA) in 185 (7.2%) and further explored. The mean time from symptom onset to CT was 100 min (range 17-300). We found a time-dependent loss of density in the occluded M1 segment within the first 5 h (N = 118, 95% CI [-15, -2], p = 0.01). Further, the thrombus area in the M2 segment decreased with time (cubic trend N = 67, 95% CI [-63, -8], p = 0.02). Overall, and especially in the M2 segment, a lower clot area was associated with higher fibrinogen (-21.7%, 95% CI [-34.8, -5.8], p = 0.009). In conclusion, our results disclosed time-dependent changes of intracranial thrombi with regard to occlusion site, density and area.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaInternational Journal of Molecular Sciences
Brojčani podacivol. 17, br. 11, str. E1959
p-ISSN1422-0067
DOIhttps://doi.org/10.3390/ijms17111959
URN:NBNurn:nbn:hr:105:397035
Datum objave publikacije2016-11-23
URL dokumentahttps://doi.org/10.3390/ijms17111959
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
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Datum i vrijeme pohrane2024-03-28 09:11:16