prikaz prve stranice dokumenta MALT1, BCL10 and FOXP1 in salivary gland mucosa-associated lymphoid tissue lymphomas
  Preuzmi
PDF 681.38 KB
Znanstveni rad - Izvorni znanstveni rad
MALT1, BCL10 and FOXP1 in salivary gland mucosa-associated lymphoid tissue lymphomas
Pathology International, 57 (2007), 1; 47-51. https://doi.org/doi: 10.1111/j.1440-1827.2007.02056.x
Borovečki, Ana; Korać, Petra; Ventura, Roland A.; Milković Periša, Marija; Banham, Alison H.; Dominis, Mara

Institucijski repozitorij: Dr Med - digitalni repozitorij Medicinskog fakulteta Sveučilišta u Zagrebu

Citirajte ovaj rad

Borovečki, A., Korać, P., Ventura, R. A., Milković Periša, M., Banham, A. H. i Dominis, M. (2007). MALT1, BCL10 and FOXP1 in salivary gland mucosa-associated lymphoid tissue lymphomas. Pathology International, 57. (1), 47-51. doi: doi: 10.1111/j.1440-1827.2007.02056.x

Borovečki, Ana, et al. "MALT1, BCL10 and FOXP1 in salivary gland mucosa-associated lymphoid tissue lymphomas." Pathology International, vol. 57, br. 1, 2007, str. 47-51. https://doi.org/doi: 10.1111/j.1440-1827.2007.02056.x

Borovečki, Ana, Petra Korać, Roland A. Ventura, Marija Milković Periša, Alison H. Banham i Mara Dominis. "MALT1, BCL10 and FOXP1 in salivary gland mucosa-associated lymphoid tissue lymphomas." Pathology International 57, br. 1 (2007): 47-51. https://doi.org/doi: 10.1111/j.1440-1827.2007.02056.x

Borovečki, A., et al. (2007) 'MALT1, BCL10 and FOXP1 in salivary gland mucosa-associated lymphoid tissue lymphomas', Pathology International, 57(1), str. 47-51. doi: doi: 10.1111/j.1440-1827.2007.02056.x

Borovečki A, Korać P, Ventura RA, Milković Periša M, Banham AH, Dominis M. MALT1, BCL10 and FOXP1 in salivary gland mucosa-associated lymphoid tissue lymphomas. Pathology International [Internet]. 01.2007. [pristupljeno 05.05.2024.];57(1):47-51. doi: doi: 10.1111/j.1440-1827.2007.02056.x

A. Borovečki, P. Korać, R. A. Ventura, M. Milković Periša, A. H. Banham i M. Dominis, "MALT1, BCL10 and FOXP1 in salivary gland mucosa-associated lymphoid tissue lymphomas", Pathology International, vol. 57, br. 1, str. 47-51, Siječanj 2007. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:125763. [Citirano: 05.05.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:125763
Podaci o radu
Naslov (engleski)MALT1, BCL10 and FOXP1 in salivary gland mucosa-associated lymphoid tissue lymphomas
AutorAna Borovečki
AutorPetra Korać
AutorRoland A. Ventura
AutorMarija Milković Periša
AutorAlison H. Banham
AutorMara Dominis
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
In view of the certain anatomic site-dependent frequency of chromosomal translocations involved in extranodal marginal zone B cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) pathogenesis, 17 salivary gland MALT lymphoma cases were analyzed for MALT1 and FOXP1 translocations. B cell CLL/lymphoma 10 (BCL10) and forkhead box PA (FOXP1) protein expression were studied by immunohistochemistry and translocations identified using fluorescence in situ hybridization (FISH)-specific probes FOXP1, t(11;18)(q21;q21)/API2-MALT1 and t(14;18)(q32;q21)/IgH-MALT1. None of the 11 analyzed cases showed FOXP1 rearrangement or amplification. The t(11;18) was present in five of 13 cases and the t(14;18) in three of 13 cases. MALT1 translocations were mostly mutually exclusive except in a single case. FOXP1 protein expression showed differences in the proportion of tumor cells with nuclear expression but not in their intensity, with the exception of one case where very intense nuclear staining was noted. BCL10 nuclear expression was present in four of 17 cases, two of which lacked t(11;18). Our results suggest that MALT1-specific translocations and FOXP1 rearrangements are not commonly involved in pathogenesis. A case with strong FOXP1 protein expression indicates the possibility that the upregulation of FOXP1 expression is significant in a small subset of salivary gland MALT lymphomas. Also a single case in which both MALT1 translocations were present indicates that these are not always mutually exclusive.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeZavršna verzija rukopisa prihvaćena za objavljivanje (postprint)
Naslov časopisaPathology International
Brojčani podacivol. 57, br. 1, str. 47-51
p-ISSN1320-5463
DOIhttps://doi.org/doi: 10.1111/j.1440-1827.2007.02056.x
URN:NBNurn:nbn:hr:105:125763
Datum objave publikacije2007-01
URL dokumentahttps://doi.org/10.1111/j.1440-1827.2007.02056.x
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2024-03-28 10:28:24