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Patient with neuromyelitis optica and inflammatory demyelinating lesions comprising whole spinal cord from C2 level till conus: case report
BMC Neurology, 9 (2009), 56; https://doi.org/10.1186/1471-2377-9-56
Petelin Gadže, Željka; Hajnšek, Sanja; Bašić, Silvio; Sporiš, Davor; Pavliša, Goran; Nanković, Sibila

Institucijski repozitorij: Dr Med - digitalni repozitorij Medicinskog fakulteta Sveučilišta u Zagrebu

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Petelin Gadže, Ž., Hajnšek, S., Bašić, S., Sporiš, D., Pavliša, G. i Nanković, S. (2009). Patient with neuromyelitis optica and inflammatory demyelinating lesions comprising whole spinal cord from C2 level till conus: case report. BMC Neurology, 9. (56). doi: 10.1186/1471-2377-9-56

Petelin Gadže, Željka, et al. "Patient with neuromyelitis optica and inflammatory demyelinating lesions comprising whole spinal cord from C2 level till conus: case report." BMC Neurology, vol. 9, br. 56, 2009. https://doi.org/10.1186/1471-2377-9-56

Petelin Gadže, Željka, Sanja Hajnšek, Silvio Bašić, Davor Sporiš, Goran Pavliša i Sibila Nanković. "Patient with neuromyelitis optica and inflammatory demyelinating lesions comprising whole spinal cord from C2 level till conus: case report." BMC Neurology 9, br. 56 (2009). https://doi.org/10.1186/1471-2377-9-56

Petelin Gadže, Ž., et al. (2009) 'Patient with neuromyelitis optica and inflammatory demyelinating lesions comprising whole spinal cord from C2 level till conus: case report', BMC Neurology, 9(56). doi: 10.1186/1471-2377-9-56

Petelin Gadže Ž, Hajnšek S, Bašić S, Sporiš D, Pavliša G, Nanković S. Patient with neuromyelitis optica and inflammatory demyelinating lesions comprising whole spinal cord from C2 level till conus: case report. BMC Neurology [Internet]. 23.10.2009. [pristupljeno 03.06.2024.];9(56). doi: 10.1186/1471-2377-9-56

Ž. Petelin Gadže, S. Hajnšek, S. Bašić, D. Sporiš, G. Pavliša i S. Nanković, "Patient with neuromyelitis optica and inflammatory demyelinating lesions comprising whole spinal cord from C2 level till conus: case report", BMC Neurology, vol. 9, br. 56, Listopad 2009. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:183139. [Citirano: 03.06.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:183139
Podaci o radu
Naslov (engleski)Patient with neuromyelitis optica and inflammatory demyelinating lesions comprising whole spinal cord from C2 level till conus: case report
AutorŽeljka Petelin Gadže
AutorSanja Hajnšek
AutorSilvio Bašić
AutorDavor Sporiš
AutorGoran Pavliša
AutorSibila Nanković
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
BACKGROUND: Neuromyelitis optica (NMO) is an idiopathic, severe, inflammatory demyelinating disease of the central nervous system, that causes severe optic neuritis and myelitis attacks. Early discrimination between multiple sclerosis (MS) and NMO is important, as optimum treatment for both diseases may differ considerably. ----- CASE PRESENTATION: We report a case of a patient who initially presented as longitudinally extensive transverse myelitis (LETM), having spastic upper extremities diparesis and spastic paraplegia, C2/C3 sensory level and urinary incontinence, as well as extensive inflammatory spinal cord lesions from C2 level to conus. After 5 months the patient had another attack of transverse myelitis, had electrophysiological findings consistent with optic neuritis, was seropositive for NMO-IgG (aquaporin-4 IgG) and thus fulfilled NMO diagnostic criteria. Following treatment of disease attacks with pulse corticosteroid therapy and intravenous immunoglobulins, we included oral azathioprine in a combination with oral prednisone in the therapy. Since there was no significant clinical improvement, we decided to use cyclophosphamide therapy, which resulted in good clinical improvement and gradual decrease of cord swelling. ----- CONCLUSION: In this NMO case report we wanted to emphasize the extensiveness of inflammatory spinal cord changes in our patient, from C2 level to conus. In the conclusion it is important to say that accurate, early diagnosis and distinction from MS is critical to facilitate initiation of immunosuppressive therapy for attack prevention.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Prikaz slučaja
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaBMC Neurology
Brojčani podacivol. 9, br. 56
p-ISSN1471-2377
DOIhttps://doi.org/10.1186/1471-2377-9-56
URN:NBNurn:nbn:hr:105:183139
Datum objave publikacije2009-10-23
URL dokumentahttps://doi.org/10.1186/1471-2377-9-56
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2024-03-28 11:28:21