prikaz prve stranice dokumenta Treatment of chronic hepatitis C in Croatian war veterans: experiences from Croatian reference center for viral hepatitis
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Treatment of chronic hepatitis C in Croatian war veterans: experiences from Croatian reference center for viral hepatitis
Croatian Medical Journal, 52 (2011), 1; 35-40. https://doi.org/10.3325/cmj.2011.52.35
Papić, Neven; Židovec Lepej, Snježana; Kurelac, Ivan; Čajić, Vjeran; Budimir, Jelena; Dušek, Davorka; Vince, Adriana

Institucijski repozitorij: Dr Med - digitalni repozitorij Medicinskog fakulteta Sveučilišta u Zagrebu

Citirajte ovaj rad

Papić, N., Židovec Lepej, S., Kurelac, I., Čajić, V., Budimir, J., Dušek, D. i Vince, A. (2011). Treatment of chronic hepatitis C in Croatian war veterans: experiences from Croatian reference center for viral hepatitis. Croatian Medical Journal, 52. (1), 35-40. doi: 10.3325/cmj.2011.52.35

Papić, Neven, et al. "Treatment of chronic hepatitis C in Croatian war veterans: experiences from Croatian reference center for viral hepatitis." Croatian Medical Journal, vol. 52, br. 1, 2011, str. 35-40. https://doi.org/10.3325/cmj.2011.52.35

Papić, Neven, Snježana Židovec Lepej, Ivan Kurelac, Vjeran Čajić, Jelena Budimir, Davorka Dušek i Adriana Vince. "Treatment of chronic hepatitis C in Croatian war veterans: experiences from Croatian reference center for viral hepatitis." Croatian Medical Journal 52, br. 1 (2011): 35-40. https://doi.org/10.3325/cmj.2011.52.35

Papić, N., et al. (2011) 'Treatment of chronic hepatitis C in Croatian war veterans: experiences from Croatian reference center for viral hepatitis', Croatian Medical Journal, 52(1), str. 35-40. doi: 10.3325/cmj.2011.52.35

Papić N, Židovec Lepej S, Kurelac I, Čajić V, Budimir J, Dušek D, i sur.. Treatment of chronic hepatitis C in Croatian war veterans: experiences from Croatian reference center for viral hepatitis. Croatian Medical Journal [Internet]. 15.02.2011. [pristupljeno 25.12.2024.];52(1):35-40. doi: 10.3325/cmj.2011.52.35

N. Papić, et al., "Treatment of chronic hepatitis C in Croatian war veterans: experiences from Croatian reference center for viral hepatitis", Croatian Medical Journal, vol. 52, br. 1, str. 35-40, Veljača 2011. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:039568. [Citirano: 25.12.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:039568
Podaci o radu
Naslov (engleski)Treatment of chronic hepatitis C in Croatian war veterans: experiences from Croatian reference center for viral hepatitis
AutorNeven Papić
AutorSnježana Židovec Lepej
AutorIvan Kurelac
AutorVjeran Čajić
AutorJelena Budimir
AutorDavorka Dušek
AutorAdriana Vince
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
Aim. To examine the risk factors, comorbidity, severity of liver disease, treatment course, and outcome in Croatian war veterans with chronic hepatitis C, especially those suffering from posttraumatic stress disorder (PTSD). ----- Methods. We collected medical records of 170 adult men diagnosed with chronic hepatitis C who started treatment with a combination of pegylated interferon-alpha and ribavirin between January 2003 and June 2009 at the Croatian Reference Centre for Viral Hepatitis. ----- Results. Participants' mean age was 43±9 years. Among 170 participants, there were 37 war veterans (22%). The main risk factor in veteran patients were operative procedures with transfusions (46% vs 5% in non-veterans; P<0.001) and in non-veteran patients intravenous drug use (42.1% vs 13%; P<0.001). The average duration of infection was longer in war veterans (14.5±3.4 vs 12.2±7.2 years; P=0.020). The percentage of PTSD comorbidity in the whole group was 11% (18/170) and in the war veterans group 49% (18/37). The prevalence of sustained virological response in patients with PTSD was 50% and in patients without PTSD 56%. Treatment reduction in patients with PTSD (33%) was higher than in patients without PTSD (12%; P=0.030). ----- Conclusion. Croatian war veterans are a group with high risk of chronic hepatitis C infection because many of them were wounded during the Croatian War 1991-1995. Considerations about PTSD as a contraindication for interferon treatment are unjustified. If treated, patients with PTSD have an equal chance of achieving sustained virological response as patients without PTSD.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCroatian Medical Journal
Brojčani podacivol. 52, br. 1, str. 35-40
p-ISSN0353-9504
DOIhttps://doi.org/10.3325/cmj.2011.52.35
URN:NBNurn:nbn:hr:105:039568
Datum objave publikacije2011-02-15
URL dokumentahttp://www.cmj.hr/2011/52/1/21328718.htm
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2024-03-28 11:59:40