prikaz prve stranice dokumenta Reactive oxygen species within the vaginal space: An additional promoter of cervical intraepithelial neoplasia and uterine cervical cancer development?
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Reactive oxygen species within the vaginal space: An additional promoter of cervical intraepithelial neoplasia and uterine cervical cancer development?
Open Medicine, 18 (2023), 1; 20230826. https://doi.org/10.1515/med-2023-0826
Despot, Albert; Fureš, Rajko; Despot, Ana-Marija; Mikuš, Mislav; Zlopaša, Gordan; D’Amato, Antonio; Chiantera, Vito; Serra, Pietro; Etrusco, Andrea; Laganà, Antonio Simone

Institucijski repozitorij: Dr Med - digitalni repozitorij Medicinskog fakulteta Sveučilišta u Zagrebu

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Despot, A., Fureš, R., Despot, A. M., Mikuš, M., Zlopaša, G., D’Amato, A. ... Laganà, A. S. (2023). Reactive oxygen species within the vaginal space: An additional promoter of cervical intraepithelial neoplasia and uterine cervical cancer development?. Open Medicine, 18. (1). doi: 10.1515/med-2023-0826

Despot, Albert, et al. "Reactive oxygen species within the vaginal space: An additional promoter of cervical intraepithelial neoplasia and uterine cervical cancer development?." Open Medicine, vol. 18, br. 1, 2023. https://doi.org/10.1515/med-2023-0826

Despot, Albert, Rajko Fureš, Ana Marija Despot, Mislav Mikuš, Gordan Zlopaša, Antonio D’Amato, Vito Chiantera, Pietro Serra, Andrea Etrusco i Antonio Simone Laganà. "Reactive oxygen species within the vaginal space: An additional promoter of cervical intraepithelial neoplasia and uterine cervical cancer development?." Open Medicine 18, br. 1 (2023). https://doi.org/10.1515/med-2023-0826

Despot, A., et al. (2023) 'Reactive oxygen species within the vaginal space: An additional promoter of cervical intraepithelial neoplasia and uterine cervical cancer development?', Open Medicine, 18(1). doi: 10.1515/med-2023-0826

Despot A, Fureš R, Despot AM, Mikuš M, Zlopaša G, D’Amato A, i sur.. Reactive oxygen species within the vaginal space: An additional promoter of cervical intraepithelial neoplasia and uterine cervical cancer development?. Open Medicine [Internet]. 21.10.2023. [pristupljeno 23.11.2024.];18(1). doi: 10.1515/med-2023-0826

A. Despot, et al., "Reactive oxygen species within the vaginal space: An additional promoter of cervical intraepithelial neoplasia and uterine cervical cancer development?", Open Medicine, vol. 18, br. 1, Listopad 2023. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:359370. [Citirano: 23.11.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:359370
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Naslov (engleski)Reactive oxygen species within the vaginal space: An additional promoter of cervical intraepithelial neoplasia and uterine cervical cancer development?
AutorAlbert Despot
AutorRajko Fureš
AutorAna-Marija Despot
AutorMislav Mikuš
AutorGordan Zlopaša
AutorAntonio D’Amato
AutorVito Chiantera
AutorPietro Serra
AutorAndrea Etrusco
AutorAntonio Simone Laganà
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA GINEKOLOGIJU I OPSTETRICIJU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Ginekologija i opstetricija
Sažetak (engleski)
Uterine cervical intraepithelial abnormalities and cancer development may also depend upon biological problems that arise as a result of complex molecular disturbances within the vaginal space, in addition to the widely known causative effect of human papillomavirus (HPV) infection. Chronic oxidative stress is a consequence of oxygen reduction in the vaginal space. Reactive oxygen species (ROS) and free radicals are yet unrecognizable causative agents and are probably very important factors for cervical intraepithelial neoplasia (CIN) and cancer development. The intermediate compounds of oxygen reduction on these metabolic pathways are superoxide anion(O2-), hydrogen peroxide (H2O2), hydroxide ions (OH-), and hydroxyl radical (HO˙). Considering these points, the aim of this work was to summarize how these compounds can damage all molecules, including DNA, of vulnerable metaplastic cervical epithelium. Finally, in some women with a poor immune defense system, ROS alone or accompanied by a high-risk HPV type may promote all levels of CIN and cancer development.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaOpen Medicine
Brojčani podacivol. 18, br. 1, 20230826
e-ISSN2391-5463
DOIhttps://doi.org/10.1515/med-2023-0826
URN:NBNurn:nbn:hr:105:359370
Datum objave publikacije2023-10-21
URL dokumentahttps://www.degruyter.com/document/doi/10.1515/med-2023-0826/html
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2024-05-17 07:39:48