Diabetes mellitus, or diabetes, is a disorder of elevated glucose levels in blood that occurs because of a disturbance in the beta cells of the pancreas, which can not produce enough insulin, or the insensitivity of cells to insulin. In the treatment of diabeteshas began to consider the increased usage and the consumption of honey. The honey is causing lower blood sugar, and it has anti-inflammatory, anti-proliferative and anti-bacterial properties. The honeybees are producing honey that can be different type, which depends on the collected floral nectar. Honey tends to decrease triglyceride and low density lipoprotein-LDL. Also notable is its antioxidant role in preventing lipid oxidation and prevention the harmful effects of free radicals. Because the presence of different substances, such as carbohydrates, organic acids, flavonoids, vitamins and minerals, honey is distinguished by its healing and beneficial effect on health. In this paper are describedthe most important effects of honey on health and diabetes, and how to be applied during the suppression of some of the complications of diabetes.