prikaz prve stranice dokumenta Genetic frequencies of paraoxonase 1 gene polymorphisms in Croatian population
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Genetic frequencies of paraoxonase 1 gene polymorphisms in Croatian population
Croatica Chemica Acta, 81 (2008), 1; 105-111. urn:nbn:hr:163:647455
Grdić, Marija; Barišić, Karmela; Rumora, Lada; Salamunić, Ilza; Tadijanović, Milena; Žanić Grubišić, Tihana; Pšikalova, Renata; Flegar-Meštrić, Zlata; Juretić, Dubravka

Institucijski repozitorij: Repozitorij Farmaceutsko-biokemijskog fakulteta Sveučilišta u Zagrebu

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Grdić, M., Barišić, K., Rumora, L., Salamunić, I., Tadijanović, M., Žanić Grubišić, T. ... Juretić, D. (2008). Genetic frequencies of paraoxonase 1 gene polymorphisms in Croatian population. Croatica Chemica Acta, 81. (1), 105-111. Preuzeto s https://urn.nsk.hr/urn:nbn:hr:163:647455

Grdić, Marija, et al. "Genetic frequencies of paraoxonase 1 gene polymorphisms in Croatian population." Croatica Chemica Acta, vol. 81, br. 1, 2008, str. 105-111. https://urn.nsk.hr/urn:nbn:hr:163:647455

Grdić, Marija, Karmela Barišić, Lada Rumora, Ilza Salamunić, Milena Tadijanović, Tihana Žanić Grubišić, Renata Pšikalova, Zlata Flegar Meštrić i Dubravka Juretić. "Genetic frequencies of paraoxonase 1 gene polymorphisms in Croatian population." Croatica Chemica Acta 81, br. 1 (2008): 105-111. https://urn.nsk.hr/urn:nbn:hr:163:647455

Grdić, M., et al. (2008) 'Genetic frequencies of paraoxonase 1 gene polymorphisms in Croatian population', Croatica Chemica Acta, 81(1), str. 105-111. Preuzeto s: https://urn.nsk.hr/urn:nbn:hr:163:647455 (Datum pristupa: 25.11.2024.)

Grdić M, Barišić K, Rumora L, Salamunić I, Tadijanović M, Žanić Grubišić T, i sur.. Genetic frequencies of paraoxonase 1 gene polymorphisms in Croatian population. Croatica Chemica Acta [Internet]. 15.04.2008. [pristupljeno 25.11.2024.];81(1):105-111. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:163:647455

M. Grdić, et al., "Genetic frequencies of paraoxonase 1 gene polymorphisms in Croatian population", Croatica Chemica Acta, vol. 81, br. 1, str. 105-111, Travanj 2008. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:163:647455. [Citirano: 25.11.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:163:647455
Podaci o radu
Naslov (engleski)Genetic frequencies of paraoxonase 1 gene polymorphisms in Croatian population
AutorMarija Grdić
AutorKarmela Barišić
AutorLada Rumora
AutorIlza Salamunić
AutorMilena Tadijanović
AutorTihana Žanić Grubišić
AutorRenata Pšikalova
AutorZlata Flegar-Meštrić
AutorDubravka Juretić
Autorova ustanovaSveučilište u Zagrebu
Farmaceutsko-biokemijski fakultet
(Zavod za medicinsku biokemiju i hematologiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Farmacija
Medicinska biokemija
Sažetak (engleski)
Paraoxonase 1 (PON1), a HDL-associated enzyme, is believed to contribute to the protective effects of HDL by decreasing the generation of lipid peroxidation products during the process of LDL oxidation. It has been reported that polymorphisms in promoter and coding regions of the pon1 gene could affect PON1 activity. The aim of this study was to determine the frequencies of pon1 polymorphisms Q192R, L55M and –108C>T and their influence on PON1 activity in healthy population of Croatia. The following genotype frequencies were determined: 60 % QQ, 34 % QR, 6 % RR for Q192R; 44 % LL, 43 % LM, 13 % MM for L55M; 30 % CC, 48 % CT, 22 % TT for –108C>T polymorphism. Genotypes RR, LL and CC were found to be associated with higher PON1 activity. The most frequent genotypes in healthy Croatian population were QQ, CT and equally present LL and LM.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCroatica Chemica Acta
Brojčani podacivol. 81, br. 1, str. 105-111
p-ISSN0011-1643
e-ISSN1334-417X
URN:NBNurn:nbn:hr:163:647455
Datum objave publikacije2008-04-15
URL dokumentahttps://hrcak.srce.hr/23398
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2018-05-11 11:33:11