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Swinging a sword : how microtubules search for their targets
Systems and Synthetic Biology, 8 (2014), 3; 179-186. https://doi.org/10.1007/s11693-014-9134-x
Pavin, Nenad; Tolić‑Nørrelykke, Iva M.

Institucijski repozitorij: Repozitorij Prirodoslovno-matematičkog fakulteta

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Pavin, N. i Tolić‑Nørrelykke, I. M. (2014). Swinging a sword : how microtubules search for their targets. Systems and Synthetic Biology, 8. (3), 179-186. doi: 10.1007/s11693-014-9134-x

Pavin, Nenad i Iva M. Tolić‑Nørrelykke. "Swinging a sword : how microtubules search for their targets." Systems and Synthetic Biology, vol. 8, br. 3, 2014, str. 179-186. https://doi.org/10.1007/s11693-014-9134-x

Pavin, Nenad i Iva M. Tolić‑Nørrelykke. "Swinging a sword : how microtubules search for their targets." Systems and Synthetic Biology 8, br. 3 (2014): 179-186. https://doi.org/10.1007/s11693-014-9134-x

Pavin, N. i Tolić‑Nørrelykke, I. M. (2014) 'Swinging a sword : how microtubules search for their targets', Systems and Synthetic Biology, 8(3), str. 179-186. doi: 10.1007/s11693-014-9134-x

Pavin N, Tolić‑Nørrelykke IM. Swinging a sword : how microtubules search for their targets. Systems and Synthetic Biology [Internet]. 2014. [pristupljeno 04.11.2024.];8(3):179-186. doi: 10.1007/s11693-014-9134-x

N. Pavin i I. M. Tolić‑Nørrelykke, "Swinging a sword : how microtubules search for their targets", Systems and Synthetic Biology, vol. 8, br. 3, str. 179-186, 2014. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:217:436716. [Citirano: 04.11.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:217:436716
Podaci o radu
Naslov (engleski)Swinging a sword : how microtubules search for their targets
AutorNenad Pavin
AutorIva M. Tolić‑Nørrelykke
Autorova ustanovaSveučilište u Zagrebu
Prirodoslovno-matematički fakultet
(Fizički odsjek)
Znanstveno / umjetničko
područje, polje i grana		PRIRODNE ZNANOSTI
Fizika
Sažetak (engleski)
The cell interior is in constant movement, which is to a large extent determined by microtubules, thin and long filaments that permeate the cytoplasm. To move large objects, microtubules need to connect them to the site of their destination. For example, during cell division, microtubules connect chromosomes with the spindle poles via kinetochores, protein complexes on the chromosomes. A general question is how microtubules, while being bound to one structure, find the target that needs to be connected to this structure. Here we review the mechanisms of how microtubules search for kinetochores, with emphasis on the recently discovered microtubule feature to explore space by pivoting around the spindle pole. In addition to accelerating the search for kinetochores, pivoting helps the microtubules to search for cortical anchors, as well as to self-organize into parallel arrays and asters to target specific regions of the cell. Thus, microtubule pivoting constitutes a mechanism by which they locate targets in different cellular contexts.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaSystems and Synthetic Biology
Brojčani podacivol. 8, br. 3, str. 179-186
p-ISSN1872-5325
e-ISSN1872-5333
DOIhttps://doi.org/10.1007/s11693-014-9134-x
URN:NBNurn:nbn:hr:217:436716
Datum objave publikacije2014
URL dokumentahttps://link.springer.com/article/10.1007/s11693-014-9134-x
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 3.0 (CC BY 3.0)
Javna napomena© The Author(s) 2014. This article is published with open access at Springerlink.com. This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. Received: 7 December 2013. Accepted: 4 February 2014. Published online: 16 February 2014.
Datum i vrijeme pohrane2019-11-29 14:51:29