prikaz prve stranice dokumenta Laser microsurgery reveals conserved viscoelastic behavior of the kinetochore
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Laser microsurgery reveals conserved viscoelastic behavior of the kinetochore
Journal of Cell Biology, 212 (2016), 7; 767-776. https://doi.org/10.1083/jcb.201506011
Cojoc, Gheorghe; Roscioli, Emanuele; Zhang, Lijuan; García-Ulloa, Alfonso; Shah, Jagesh V.; Berns, Michael W.; Pavin, Nenad; Cimini, Daniela; Tolić, Iva Marija; Gregan, Juraj

Institucijski repozitorij: Repozitorij Prirodoslovno-matematičkog fakulteta

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Cojoc, G., Roscioli, E., Zhang, L., García Ulloa, A., Shah, J. V., Berns, M. W. ... Gregan, J. (2016). Laser microsurgery reveals conserved viscoelastic behavior of the kinetochore. Journal of Cell Biology, 212. (7), 767-776. doi: 10.1083/jcb.201506011

Cojoc, Gheorghe, et al. "Laser microsurgery reveals conserved viscoelastic behavior of the kinetochore." Journal of Cell Biology, vol. 212, br. 7, 2016, str. 767-776. https://doi.org/10.1083/jcb.201506011

Cojoc, Gheorghe, Emanuele Roscioli, Lijuan Zhang, Alfonso García Ulloa, Jagesh V. Shah, Michael W. Berns, Nenad Pavin, Daniela Cimini, Iva Marija Tolić i Juraj Gregan. "Laser microsurgery reveals conserved viscoelastic behavior of the kinetochore." Journal of Cell Biology 212, br. 7 (2016): 767-776. https://doi.org/10.1083/jcb.201506011

Cojoc, G., et al. (2016) 'Laser microsurgery reveals conserved viscoelastic behavior of the kinetochore', Journal of Cell Biology, 212(7), str. 767-776. doi: 10.1083/jcb.201506011

Cojoc G, Roscioli E, Zhang L, García Ulloa A, Shah JV, Berns MW, i sur.. Laser microsurgery reveals conserved viscoelastic behavior of the kinetochore. Journal of Cell Biology [Internet]. 2016. [pristupljeno 27.12.2024.];212(7):767-776. doi: 10.1083/jcb.201506011

G. Cojoc, et al., "Laser microsurgery reveals conserved viscoelastic behavior of the kinetochore", Journal of Cell Biology, vol. 212, br. 7, str. 767-776, 2016. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:217:574387. [Citirano: 27.12.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:217:574387
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Naslov (engleski)Laser microsurgery reveals conserved viscoelastic behavior of the kinetochore
AutorGheorghe Cojoc
AutorEmanuele Roscioli
AutorLijuan Zhang
AutorAlfonso García-Ulloa
AutorJagesh V. Shah
AutorMichael W. Berns
AutorNenad Pavin
MBZ: 204800
AutorDaniela Cimini
AutorIva Marija Tolić
MBZ: 260543
AutorJuraj Gregan
Autorova ustanovaSveučilište u Zagrebu
Prirodoslovno-matematički fakultet
(Fizički odsjek)
Znanstveno / umjetničko
područje, polje i grana		PRIRODNE ZNANOSTI
Fizika
Znanstveno / umjetničko
područje, polje i grana		PRIRODNE ZNANOSTI
Biologija
Sažetak (engleski)
Accurate chromosome segregation depends on proper kinetochore– microtubule attachment. Upon microtubule interaction, kinetochores are subjected to forces generated by the microtubules. In this work, we used laser ablation to sever microtubules attached to a merotelic kinetochore, which is laterally stretched by opposing pulling forces exerted by microtubules, and inferred the mechanical response of the kinetochore from its length change. In both mammalian PtK1 cells and in the fission yeast Schizosaccharomyces pombe, kinetochores shortened after microtubule severing. Interestingly, the inner kinetochore–centromere relaxed faster than the outer kinetochore. Whereas in fission yeast all kinetochores relaxed to a similar length, in PtK1 cells the more stretched kinetochores remained more stretched. Simple models suggest that these differences arise because the mechanical structure of the mammalian kinetochore is more complex. Our study establishes merotelic kinetochores as an experimental model for studying the mechanical response of the kinetochore in live cells and reveals a viscoelastic behavior of the kinetochore that is conserved in yeast and mammalian cells.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaJournal of Cell Biology
Brojčani podacivol. 212, br. 7, str. 767-776
p-ISSN0021-9525
e-ISSN1540-8140
DOIhttps://doi.org/10.1083/jcb.201506011
URN:NBNurn:nbn:hr:217:574387
Datum objave publikacije2016
URL dokumentahttps://rupress.org/jcb/article/212/7/767/38423/Laser-microsurgery-reveals-conserved-viscoelastic
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno-Dijeli pod istim uvjetima 3.0 (CC BY-NC-SA 3.0)
Javna napomena© 2016 Cojoc et al. This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/). Submitted: June 2, 2015. Accepted: February 25, 2016. Published March 21, 2016. Šifre projekata: RGY0069/2010, MCB- 0842551, MCB-1517506, P21437, P23609, EC (PCIG11-GA-2012-322300), APVV (APVV- 0334-12), VEGA (1/0196/14)
Datum i vrijeme pohrane2020-02-23 13:39:31