prikaz prve stranice dokumenta In vivo assessment of genotoxicity in buccal cells of children undergoing tooth restoration
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In vivo assessment of genotoxicity in buccal cells of children undergoing tooth restoration
Central European Journal of Public Health, 27 (2019), 4; 312-319. https://doi.org/10.21101/cejph.a5216
Gavić, Lidia; Goršeta, Kristina; Glavina, Domagoj; Željezić, Davor; Galić, Nada; Tadin, Antonija

Institucijski repozitorij: Repozitorij stomatološkog fakulteta u Zagrebu

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Gavić, L., Goršeta, K., Glavina, D., Željezić, D., Galić, N. i Tadin, A. (2019). In vivo assessment of genotoxicity in buccal cells of children undergoing tooth restoration. Central European Journal of Public Health, 27. (4), 312-319. doi: 10.21101/cejph.a5216

Gavić, Lidia, et al. "In vivo assessment of genotoxicity in buccal cells of children undergoing tooth restoration." Central European Journal of Public Health, vol. 27, br. 4, 2019, str. 312-319. https://doi.org/10.21101/cejph.a5216

Gavić, Lidia, Kristina Goršeta, Domagoj Glavina, Davor Željezić, Nada Galić i Antonija Tadin. "In vivo assessment of genotoxicity in buccal cells of children undergoing tooth restoration." Central European Journal of Public Health 27, br. 4 (2019): 312-319. https://doi.org/10.21101/cejph.a5216

Gavić, L., et al. (2019) 'In vivo assessment of genotoxicity in buccal cells of children undergoing tooth restoration', Central European Journal of Public Health, 27(4), str. 312-319. doi: 10.21101/cejph.a5216

Gavić L, Goršeta K, Glavina D, Željezić D, Galić N, Tadin A. In vivo assessment of genotoxicity in buccal cells of children undergoing tooth restoration. Central European Journal of Public Health [Internet]. 31.12.2019. [pristupljeno 23.11.2024.];27(4):312-319. doi: 10.21101/cejph.a5216

L. Gavić, K. Goršeta, D. Glavina, D. Željezić, N. Galić i A. Tadin, "In vivo assessment of genotoxicity in buccal cells of children undergoing tooth restoration", Central European Journal of Public Health, vol. 27, br. 4, str. 312-319, Prosinac 2019. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:127:502600. [Citirano: 23.11.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:127:502600
Podaci o radu
Naslov (engleski)In vivo assessment of genotoxicity in buccal cells of children undergoing tooth restoration
AutorLidia Gavić
AutorKristina Goršeta
AutorDomagoj Glavina
AutorDavor Željezić
AutorNada Galić
MBZ: 192110
AutorAntonija Tadin
Autorova ustanovaInstitut za medicinska istraživanja i medicinu rada
Autorova ustanova(Klinički bolnički centar Zagreb)
Autorova ustanovaSveučilište u Splitu
Medicinski fakultet
Autorova ustanovaSveučilište u Zagrebu
Stomatološki fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Dentalna medicina
Sažetak (engleski)
Objectives: Whereas dental materials came in direct or close contact with oral tissue, it is a great concern about the biocompatibility of those materials. This study was performed to evaluate possible DNA damage to buccal cells exposed to dental materials. Methods: This prospective, longitudinal clinical study was conducted over a three months period. Class II restorations were placed in 60 young patients with no previous filling using one of three tested dental materials (two glass ionomers; Ketac Molar and Ionofil Molar and one compomer material; Twinky Star). DNA damage was analysed by micronucleus assays, in buccal exfoliated epithelial cells. Results: In patients treated with Ketac Molar, a significant frequency of micronuclei (p = 0.027) and binucleated cells in samples taken 30 days following restoration (p = 0.029) was confirmed. In patients treated with Twinky Star, a statistically significant increase in the number of binucleated cells in samples taken after 7 and 30 days following restoration (p = 0.001 and p < 0.001, respectively) was observed. In all samples collected 90 days after treatment, there was no statistical difference in the number of any cell changes. Conclusion: In this study long-term biocompatibility of tested materials was confirmed. Glass ionomers and compomers are widely used materials in paediatric dentistry, and this study has proved their safety for usage in children.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCentral European Journal of Public Health
Brojčani podacivol. 27, br. 4, str. 312-319
p-ISSN1210-7778
e-ISSN1803-1048
DOIhttps://doi.org/10.21101/cejph.a5216
URN:NBNurn:nbn:hr:127:502600
Datum objave publikacije2019-12-31
URL dokumentahttp://cejph.szu.cz/doi/10.21101/cejph.a5216.html
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2024-10-24 07:34:41